Historical and current perspectives on Clostridium botulinum diversity

Details

• Alternative Title:
  Res Microbiol
• Personal Author:
  Smith, Theresa J. ; Hill, Karen K. ; Raphael, Brian H.
• Description:
  For nearly one hundred years, researchers have attempted to categorize botulinum neurotoxin-producing clostridia and the toxins that they produce according to biochemical characterizations, serological comparisons, and genetic analyses. Throughout this period the bacteria and their toxins have defied such attempts at categorization. Below is a description of both historic and current Clostridium botulinum strain and neurotoxin information that illustrates how each new finding has significantly added to the knowledge of the botulinum neurotoxin-containing clostridia and their diversity.
• Subjects:
  Bacterial Typing Techniques Botulinum Toxins Clostridium Botulinum Genetic Variation History, 20th Century History, 21st Century Molecular Typing Serotyping
• Keywords:
  Botulinum Neurotoxins Genomics Serotype
• Source:
  Res Microbiol. 166(4):290-302
• Pubmed ID:
  25312020
• Pubmed Central ID:
  PMC11302483
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  166
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:af82a92a33f53bbbf9e8efa22820580273824399c8c6a28f2769e8be1ed917ad8988d40b0ca35bf94f47c221a8df0fb244f8c091637f38f3d8d7564be62e9cdb
• Download URL:
  https://stacks.cdc.gov/view/cdc/159607/cdc_159607_DS1.pdf
• File Type:
  [PDF - 389.21 KB ]