Prevalence and risk factors of tuberculosis disease in South African correctional facilities in 2015

Details

• Alternative Title:
  Int J Tuberc Lung Dis
• Personal Author:
  Jordan, A. M. ; Podewils, L. J. ; Castro, K. G. ; Zishiri, V. ; Charalambous, S.
• Description:
  SETTING:
  
  Sixteen South African correctional facilities.
  
  OBJECTIVE:
  
  To determine the prevalence of and risk factors for tuberculosis (TB) in South African correctional facilities using data collected during a TB screening program in South African correctional facilities in 2015.
  
  DESIGN:
  
  Inmates in 16 South African correctional facilities were screened for TB from January to December 2015. Inmates reporting ≥1 TB symptom or having an abnormal computer-assisted digital chest X-ray (CXR) provided sputum. Abnormal CXRs were interpreted by a radiologist. Sputum was tested for Mycobacterium tuberculosis using Xpert® MTB/RIF. Data from 16 South African correctional facilities were used in regression analysis, and prevalence estimates calculated for 12 South African correctional facilities with >30% screening coverage.
  
  RESULTS:
  
  In 12 South African correctional facilities included in the prevalence estimates, 837 inmates had TB disease (2653/100000) as indicated by current TB treatment or screening-identified TB by radiologist or Xpert. Previous TB was associated with increased odds of screening-identified TB in HIV-positive inmates (OR 4.3, 95%CI 2.5–7.3). For HIV-negative inmates, previous TB (adjusted OR [aOR] 4.9, 95%CI 1.7–14.1) and self-reported symptoms vs. none (1 symptom, aOR 8.8, 95%CI 1.2–67.7; >2 symptoms, aOR 21.7, 95%CI 3.0–158.8) were independently associated with increased odds of screening-identified TB.
  
  CONCLUSIONS:
  
  Routine TB screening, including CXR, is needed in South African correctional facilities to identify and refer inmates with active TB.
  
  
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Female HIV Infections Humans Logistic Models Male Mass Screening Middle Aged Multivariate Analysis Mycobacterium Tuberculosis Prevalence Prisoners Radiography, Thoracic Risk Factors South Africa Sputum Tuberculosis, Pulmonary Young Adult

  More +
• Keywords:
  Correctional Facilities Prisons Risk Factors Sub-Saharan Africa TB
• Source:
  Int J Tuberc Lung Dis. 23(11):1198-1204
• Pubmed ID:
  31718756
• Pubmed Central ID:
  PMC11276119
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  23
• Issue:
  11
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:6f34ed46c83ffc0ce494c17a53b43d9d177fc9d8914cd38384669ccb55bbe15f7f4cc248679fb49b4072dfd19b7a42fd11402c5ac9ce50136edbfaeb3d9abaf2
• Download URL:
  https://stacks.cdc.gov/view/cdc/159427/cdc_159427_DS1.pdf
• File Type:
  [PDF - 522.08 KB ]