Multisystem Inflammatory Syndrome in Children (MIS-C) Among Persons who Completed a Two-Dose COVID-19 Vaccine Primary Series Compared with those Reporting No COVID-19 Vaccination, U.S. National MIS-C Surveillance

Details

• Alternative Title:
  Pediatr Infect Dis J
• Personal Author:
  Yousaf, Anna R. ; Miller, Allison D. ; Lindsey, Katherine ; Shah, Ami B. ; Wu, Michael J. ; Melgar, Michael ; Zambrano, Laura D. ; Campbell, Angela P.
• Description:
  We analyzed multisystem inflammatory syndrome in children cases by reported COVID-19 vaccination status (2-dose primary series vs. no vaccination). A total of 46% vaccinated versus 58% unvaccinated persons received intensive care unit-level care ( P = 0.02); the risk of intensive care unit admission was 23% higher (adjusted relative risk: 1.23; 95% confidence interval: 1.03-1.48) among unvaccinated patients; 21 unvaccinated persons died. Multisystem inflammatory syndrome in children occurs after SARS-CoV-2 infection in vaccinated persons, but may be less severe.
• Subjects:
  Child COVID-19 COVID-19 Vaccines Humans SARS-CoV-2 Vaccination
• Keywords:
  Children MIS-C Vaccine
• Source:
  Pediatr Infect Dis J. 42(12):e476-e478
• Pubmed ID:
  37725819
• Pubmed Central ID:
  PMC11262462
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  42
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:f520af5f3088270dcc06a7c9a4c19524c4563b753284629c2334a9864ad062c91eb36019bcbef4d7c6b7a4ec9e4f7c28b3d49a1120480277faf93f948baed4d0
• Download URL:
  https://stacks.cdc.gov/view/cdc/159341/cdc_159341_DS1.pdf
• File Type:
  [PDF - 73.87 KB ]