A latent class analysis of drug and substance use patterns among patients treated in emergency departments for suspected drug overdose

Details

• Alternative Title:
  Addict Behav
• Personal Author:
  Liu, Stephen ; Vivolo-Kantor, Alana
• Description:
  Introduction:
  
  Polysubstance use and misuse can increase risks for nonfatal and fatal drug overdose. To categorize drugs used in combination in nonfatal overdoses, we analyzed data from emergency department (ED) overdose-related visits in 18 states funded by CDC’s Enhanced State Opioid Overdose Surveillance (ESOOS) program.
  
  Methods:
  
  From 2017 to 2018, 120,706 ED visits included at least one hospital discharge code indicating acute drug poisoning for opioids, stimulants, hallucinogens, cannabis, anti-depressants, sedatives, alcohol, benzodiazepines, or other psychotropic drugs. Latent class analyses were conducted to determine the groupings of drug combinations in overdose visits.
  
  Results:
  
  Latent class analyses indicated a model of 5 classes – mostly heroin overdose (42.5% of visits); mostly non-heroin opioid overdose/use (27.3%); opioid, polysubstance (11.0%); female, younger (< 25 years), other non-opioid drugs (10.5%); female, older (> 55 years), benzodiazepine (8.0%). Findings indicated that heroin continues to be a large burden to EDs, yet EDs are also seeing overdose survivors with polydrug toxicity.
  
  Conclusions:
  
  Medication-assisted treatment could be initiated in the emergency department following overdose for patients with opioid use disorder, and post-overdose protocols, such as naloxone provision and linkage to treatment and harm reduction services, have the potential to prevent future overdose for those at risk.
  
  
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Age Factors Child Drug Overdose Emergency Service, Hospital Female Humans Latent Class Analysis Male Middle Aged Sex Factors Substance-Related Disorders United States Young Adult

  More +
• Keywords:
  Drug Overdose Emergency Department Opioid Polysubstance Use
• Source:
  Addict Behav. 101:106142
• Pubmed ID:
  31639639
• Pubmed Central ID:
  PMC11218817
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  101
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:bd2534e26ea92f18044b548ef78f9fa7578b88b50acdc789f924e3474d2590b4
• Download URL:
  https://stacks.cdc.gov/view/cdc/158486/cdc_158486_DS1.pdf
• File Type:
  [PDF - 454.65 KB ]