Development and Evaluation of a Structured Guide to Assess the Preventability of Hospital-onset Bacteremia and Fungemia

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Schrank, Gregory M. ; Sick-Samuels, Anna ; Bleasdale, Susan C. ; Jacob, Jesse T. ; Dantes, Raymund ; Gokhale, Runa H. ; Mayer, Jeanmarie ; Mehrotra, Preeti ; Mehta, Sapna A. ; Mena Lora, Alfredo J. ; Ray, Susan M. ; Rhee, Chanu ; Salinas, Jorge L. ; Seo, Susan K. ; Shane, Andi L. ; Nadimpalli, Gita ; Milstone, Aaron M. ; Robinson, Gwen ; Brown, Clayton H. ; Harris, Anthony D. ; Leekha, Surbhi
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• Corporate Authors:
  CDC Prevention Epicenters Program
• Description:
  Objective ; To assess preventability of hospital-onset bacteremia and fungemia (HOB), we developed and evaluated a structured rating guide accounting for intrinsic patient and extrinsic healthcare-related risks. ; Design ; HOB preventability rating guide was compared against a reference standard expert panel. ; Participants ; Ten-member panel of clinical experts as the standard of preventability assessment. Two physician reviewers applied the rating guide for comparison. ; Methods ; The expert panel independently rated 82 hypothetical HOB scenarios using a 6-point Likert scale, collapsed into 3 categories: Preventable, Uncertain, or Not preventable. Consensus was defined as concurrence on the same category among ≥70% experts. Scenarios without consensus were deliberated, followed by a second round of rating. ; Results ; Expert panel consensus criteria were met for 52 scenarios (63%) after two rounds. ; Conclusions ; Preventability ratings of HOB scenarios by two reviewers using a rating guide matched expert consensus in most cases with moderately high inter-reviewer reliability. While diversity of expert opinions and uncertainty of preventability merit further exploration, this is a step towards standardized assessment of HOB preventability.
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• Subjects:
  • Humans
  • Fungemia
  • Reproducibility of Results
  • Hospitals
  • Bacteremia
  • Physicians
• Keywords:
  • Healthcare-associated infections
  • preventability
  • health care quality
  • Alzheimer's disease
  • Alzheimer's disease sequencing project
  • antiviral agents
  • herpes simplex
  • human papillomavirus
  • torque teno viruses
  • whole exome sequencing
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• Source:
  Infect Control Hosp Epidemiol. 43(10):1326-1332
• Pubmed ID:
  35086601
• Pubmed Central ID:
  PMC9472698
• Document Type:
  Journal Article
• Funding:
  P30 CA008748/CA/NCI NIH HHSUnited States/ ; U01 CK000556/CK/NCEZID CDC HHSUnited States/ ; U01CK000556/ACL/ACL HHSUnited States/
• Volume:
  43
• Issue:
  10
• Download URL:
  https://stacks.cdc.gov/view/cdc/158067/cdc_158067_DS1.pdf
• File Type:
  [PDF - 568.16 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:60f8a122d72db1b21b85238b5e87a028ecb81db1815536480993e4daf448833b8074bd8094c652739dcc6c09142e8d77500e2b386e5ece5f6370bdc201c20d24