Development and Evaluation of a Structured Guide to Assess the Preventability of Hospital-onset Bacteremia and Fungemia

Details

• Alternative Title:
  Infect Control Hosp Epidemiol
• Personal Author:
  Schrank, Gregory M. ; Sick-Samuels, Anna ; Bleasdale, Susan C. ; Jacob, Jesse T. ; Dantes, Raymund ; Gokhale, Runa H. ; Mayer, Jeanmarie ; Mehrotra, Preeti ; Mehta, Sapna A. ; Mena Lora, Alfredo J. ; Ray, Susan M. ; Rhee, Chanu ; Salinas, Jorge L. ; Seo, Susan K. ; Shane, Andi L. ; Nadimpalli, Gita ; Milstone, Aaron M. ; Robinson, Gwen ; Brown, Clayton H. ; Harris, Anthony D. ; Leekha, Surbhi
• Corporate Authors:
  CDC Prevention Epicenters Program
• Description:
  Objective
  
  To assess preventability of hospital-onset bacteremia and fungemia (HOB), we developed and evaluated a structured rating guide accounting for intrinsic patient and extrinsic healthcare-related risks.
  
  Design
  
  HOB preventability rating guide was compared against a reference standard expert panel.
  
  Participants
  
  Ten-member panel of clinical experts as the standard of preventability assessment. Two physician reviewers applied the rating guide for comparison.
  
  Methods
  
  The expert panel independently rated 82 hypothetical HOB scenarios using a 6-point Likert scale, collapsed into 3 categories: Preventable, Uncertain, or Not preventable. Consensus was defined as concurrence on the same category among ≥70% experts. Scenarios without consensus were deliberated, followed by a second round of rating.
  
  Results
  
  Expert panel consensus criteria were met for 52 scenarios (63%) after two rounds.
  
  Conclusions
  
  Preventability ratings of HOB scenarios by two reviewers using a rating guide matched expert consensus in most cases with moderately high inter-reviewer reliability. While diversity of expert opinions and uncertainty of preventability merit further exploration, this is a step towards standardized assessment of HOB preventability.
  
  
• Subjects:
  Bacteremia Fungemia Hospitals Humans Physicians Reproducibility Of Results
• Keywords:
  Alzheimer's Disease Alzheimer's Disease Sequencing Project Antiviral Agents Healthcare-associated Infections Health Care Quality Herpes Simplex Human Papillomavirus Preventability Torque Teno Viruses Whole Exome Sequencing Whole Genome Sequencing

  More +
• Source:
  Infect Control Hosp Epidemiol. 43(10):1326-1332
• Pubmed ID:
  35086601
• Pubmed Central ID:
  PMC9472698
• Document Type:
  Journal Article
• Funding:
  P30 CA008748/CA/NCI NIH HHSUnited States/ ; U01 CK000556/CK/NCEZID CDC HHSUnited States/ ; U01CK000556/ACL/ACL HHSUnited States/
• Volume:
  43
• Issue:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:60f8a122d72db1b21b85238b5e87a028ecb81db1815536480993e4daf448833b8074bd8094c652739dcc6c09142e8d77500e2b386e5ece5f6370bdc201c20d24
• Download URL:
  https://stacks.cdc.gov/view/cdc/158067/cdc_158067_DS1.pdf
• File Type:
  [PDF - 568.16 KB ]