Evidence of Early Household Transmission of SARS-CoV-2 Involving a School-Aged Child

Temte, Jonathan L.; Barlow, Shari; Temte, Emily; Goss, Maureen; Florek, Kelsey; Braun, Katrina; Friedrich, Thomas C.; Reisdorf, Erik; Bateman, Allen C.; Uzicanin, Amra

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Evidence of Early Household Transmission of SARS-CoV-2 Involving a School-Aged Child

Supporting Files

10 2021
By Temte, Jonathan L. ; Barlow, Shari ; Temte, Emily ; ...

File Language:

English

Details

Alternative Title:

WMJ
Personal Author:

Temte, Jonathan L. ; Barlow, Shari ; Temte, Emily ; Goss, Maureen ; Florek, Kelsey ; Braun, Katrina ; Friedrich, Thomas C. ; Reisdorf, Erik ; Bateman, Allen C. ; Uzicanin, Amra
Description:

Introduction:

Little is known about the role of school-aged children and household transmission at the start of the SARS-CoV-2 pandemic. To evaluate for SARS-CoV-2 in school-aged children and assess household transmission, we performed reverse transcription polymerase chain reaction on 670 archived specimens that were collected between September 1, 2019 and June 30, 2020 as part of a community-based study.

Case Presentation:

A single SARS-CoV-2 case was detected in an 11-year-old girl on March 18, 2020, resulting in very low prevalence (0.15% [95% CI, 0.03–0.84]) in this population. This case was associated with SARS-CoV-2 detection in all other household members. Symptoms were reported as mild to moderate. Whole genome sequencing supported household transmission of near-identical viruses within the 19B clade.

Discussion:

This case represents the earliest known household cluster of SARS-CoV2 in Wisconsin.

Conclusion:

This case suggests that household transmission associated with school-aged children may have contributed to wide seeding across populations.
Subjects:

Child COVID-19 Female Humans Pandemics RNA, Viral SARS-CoV-2 Schools
Source:

WMJ. 120(3):233-236
Pubmed ID:

34710308
Pubmed Central ID:

PMC8721881
Document Type:

Journal Article
Funding:

F30 AI145182/AI/NIAID NIH HHSUnited States/ ; T32 GM140935/GM/NIGMS NIH HHSUnited States/ ; U01 CK000542/CK/NCEZID CDC HHSUnited States/ ; U01CK000542/ACL/ACL HHSUnited States/
Volume:

120
Issue:

3
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha256:42a958f157e5259d448ddd716729ab33f0ed6daef5104ed1a057340e9417c753
Download URL:

https://stacks.cdc.gov/view/cdc/158056/cdc_158056_DS1.pdf
File Type:

[PDF - 445.38 KB ]

File Language:

English

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