Adverse Health Outcomes among Rural Prostate Cancer Survivors: A Population-based Study

Details

• Alternative Title:
  Cancer Epidemiol
• Personal Author:
  Huang, Daren ; Chang, Chun-Pin Esther ; Newman, Michael ; Deshmukh, Vikrant ; Snyder, John ; Date, Ankita ; Galvao, Carlos ; Lloyd, Shane ; Henry, N. Lynn ; O’Neil, Brock ; Hashibe, Mia
• Description:
  Introduction:
  
  Rural cancer survivors experience considerable health disparities compared to urban cancer survivors for cancer treatment and survival. The objective of our study was to investigate the risk of developing diseases for rural compared to urban prostate cancer survivors in Utah.
  
  Methods:
  
  We identified a cohort of 3,575 rural prostate cancer survivors and 17,778 urban prostate cancer survivors from the Utah Cancer Registry. The Fine-Gray subdistribution hazards model was used to estimate hazard ratios and 95% confidence intervals for diseases in major body systems among rural compared to urban prostate cancer survivors at >1 to 5 years and >5 years after prostate cancer diagnosis.
  
  Results:
  
  Rural residence was associated with an increased risk of diseases of the respiratory system at >5 years (HR: 1.16, 95% CI: 1.01-1.32) after cancer diagnosis compared to urban residence among prostate cancer survivors in Utah. Decreased risks were observed in infectious and parasitic diseases, diseases of the blood and blood-forming organs, diseases of the nervous system and sense organs, and diseases of the skin and subcutaneous tissue for rural prostate cancer survivors between 1 to 5 years after cancer diagnosis.
  
  Conclusions:
  
  Rural prostate cancer survivors in Utah were somewhat healthier compared to urban prostate cancer survivors. Further studies are needed to confirm whether these associations are also supported for rural prostate cancer survivors in other regions of the U.S.
  
  
• Subjects:
  Cancer Survivors Humans Male Outcome Assessment, Health Care Prostate Prostatic Neoplasms Rural Population Urban Population
• Keywords:
  Comorbid Disease Health Disparity Prostate Cancer Survivors Respiratory System Rural Health
• Source:
  Cancer Epidemiol. 86:102430
• Pubmed ID:
  37473579
• Pubmed Central ID:
  PMC11150278
• Document Type:
  Journal Article
• Funding:
  R01 RR021746/RR/NCRR NIH HHSUnited States/ ; HHSN261201800016C/CA/NCI NIH HHSUnited States/ ; NU58DP007131/CC/CDC HHSUnited States/ ; HHSN261201800016I/CA/NCI NIH HHSUnited States/ ; R01 CA244326/CA/NCI NIH HHSUnited States/ ; S10 OD021644/OD/NIH HHSUnited States/ ; P30 CA042014/CA/NCI NIH HHSUnited States/
• Volume:
  86
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:1bf854c14699207be4fd44e18d625e1667ffc2631ebfd80c12fee2db3488e596
• Download URL:
  https://stacks.cdc.gov/view/cdc/157933/cdc_157933_DS1.pdf
• File Type:
  [PDF - 137.04 KB ]