Details:

• Alternative Title:
  Aerosol Sci Technol
• Personal Author:
  Zhang, Yuetong ; Shankar, Sripriya Nannu ; Vass, William B. ; Lednicky, John A. ; Fan, Z. Hugh ; ... More +

  Zhang, Yuetong ; Shankar, Sripriya Nannu ; Vass, William B. ; Lednicky, John A. ; Fan, Z. Hugh ; Agdas, Duzgun ; Makuch, Robert ; Wu, Chang-Yu Less -
• Description:
  As SARS-CoV-2 swept across the globe, increased ventilation and implementation of air cleaning were emphasized by the US CDC and WHO as important strategies to reduce the risk of inhalation exposure to the virus. To assess whether higher ventilation and air cleaning rates lead to lower exposure risk to SARS-CoV-2, 1274 manuscripts published between April 2020 and September 2022 were screened using key words "airborne SARS-CoV-2 or "SARS-CoV-2 aerosol". Ninety-three studies involved air sampling at locations with known sources (hospitals and residences) were selected and associated data were compiled. Two metrics were used to assess exposure risk: SARS-CoV-2 concentration and SARS-CoV-2 detection rate in air samples. Locations were categorized by type (hospital or residence) and proximity to the sampling location housing the isolated/quarantined patient (primary or secondary). The results showed that hospital wards had lower airborne virus concentrations than residential isolation rooms. A negative correlation was found between airborne virus concentrations in primary-occupancy areas and air changes per hour (ACH). In hospital settings, sample positivity rates were significantly reduced in secondary-occupancy areas compared to primary-occupancy areas, but they were similar across sampling locations in residential settings. ACH and sample positivity rates were negatively correlated, though the effect was diminished when ACH values exceeded 8. While limitations associated with diverse sampling protocols exist, data considered by this meta-analysis support the notion that higher ACH may reduce exposure risks to the virus in ambient air.
• Source:
  Aerosol Sci Technol. 58(3):217-243
• Pubmed ID:
  38764553
• Pubmed Central ID:
  PMC11101186
• Document Type:
  Journal Article
• Funding:
  R21 OH012114/OH/NIOSH CDC HHSUnited States/ ; R43 AI157123/AI/NIAID NIH HHSUnited States/ ; UL1 TR001427/TR/NCATS NIH HHSUnited States/ ; R01 AI158868/AI/NIAID NIH HHSUnited States/ ; TL1 TR001428/TR/NCATS NIH HHSUnited States/

  R21 OH012114/OH/NIOSH CDC HHSUnited States/ ; R43 AI157123/AI/NIAID NIH HHSUnited States/ ; UL1 TR001427/TR/NCATS NIH HHSUnited States/ ; R01 AI158868/AI/NIAID NIH HHSUnited States/ ; TL1 TR001428/TR/NCATS NIH HHSUnited States/ Less -
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  [+]

  urn:sha-512:f84d1060b9bdc2587fc8bc6236276c281ebf9fc4127de796f5489ae598e3c193a5bed94fe6345a5f9e9fb5dfd58043eeea8fc21dcb126fa068e33d1a901da422
• File Type:

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