CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners.
As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.
i
Genomic Epidemiology as a Public Health Tool to Combat Mosquito-Borne Virus Outbreaks
-
3 28 2020
-
-
Source: J Infect Dis. 221(Suppl 3):S308-S318
[PDF-880.28 KB]
Details:
-
Alternative Title:J Infect Dis
-
Personal Author:
-
Description:Next-generation sequencing technologies, exponential increases in the availability of virus genomic data, and ongoing advances in phylogenomic methods have made genomic epidemiology an increasingly powerful tool for public health response to a range of mosquito-borne virus outbreaks. In this review, we offer a brief primer on the scope and methods of phylogenomic analyses that can answer key epidemiological questions during mosquito-borne virus public health emergencies. We then focus on case examples of outbreaks, including those caused by dengue, Zika, yellow fever, West Nile, and chikungunya viruses, to demonstrate the utility of genomic epidemiology to support the prevention and control of mosquito-borne virus threats. We extend these case studies with operational perspectives on how to best incorporate genomic epidemiology into structured surveillance and response programs for mosquito-borne virus control. Many tools for genomic epidemiology already exist, but so do technical and nontechnical challenges to advancing their use. Frameworks to support the rapid sharing of multidimensional data and increased cross-sector partnerships, networks, and collaborations can support advancement on all scales, from research and development to implementation by public health agencies.
-
Subjects:
-
Keywords:
-
Source:
-
Pubmed ID:31711190
-
Pubmed Central ID:PMC11095994
-
Document Type:
-
Funding:
-
Volume:221
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
