Biosafety Laboratory Guidance for Handling and Processing Mpox Specimens
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Biosafety Laboratory Guidance for Handling and Processing Mpox Specimens

Filetype[PDF-253.76 KB]


English
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  • Corporate Authors:
    National Center for Emerging and Zoonotic Infectious Diseases (U.S.). Division of High-Consequence Pathogens and Pathology.
  • Description:
    Updated April 4, 2024

    Partners at the U.S. Department of Transportation, Labor, and Defense departments, the U.S. Environmental Protection Agency, CDC, and the Assistant Secretary for Preparedness and Response have updated released a Safety Advisory Notice regarding the classification of Monkeypox virus (MPXV) diagnostic specimens. This notice clarifies that samples from both clade I and II MPXV are designated as Category B infectious substances. Only samples or clinical waste from cultures of clade I MPXV should be designated as Category A infectious substances. Category B (UN3373) categorization includes infectious substances transported for diagnostic or investigational purposes. Submitters should follow all appropriate Category B regulations for packaging and transporting specimens from suspect mpox patients for diagnostic testing.

  • Content Notes:
    General Guidance -- Select Agent Regulations -- Select Agent Destruction and Inactivation Options -- Biosafety Considerations for Diagnostic Testing -- Routine Diagnostic Testing -- Culturing Specimens for Monkeypox Virus -- Molecular Testing and Analysis of Bacterial or Mycotic Cultures -- Clinical and Anatomic Pathology -- Environmental Testing -- Procedures with a High Likelihood of Generating Aerosols -- Decontamination -- Laboratory Waste Management -- Resources for Monitoring Healthcare Workers Exposed to Monkeypox Virus --
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    Webpage
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