Interrelationships among age at adiposity rebound, BMI during childhood, and BMI after age 14 years in an electronic health record database

Details

• Alternative Title:
  Obesity (Silver Spring)
• Personal Author:
  Freedman, David S. ; Goodwin-Davies, Amy J. ; Kompaniyets, Lyudmyla ; Lange, Samantha J. ; Goodman, Alyson B. ; Phan, Thao-Ly Tam ; Rao, Suchitra ; Eneli, Ihuoma ; Forrest, Christopher B.
• Description:
  Objective:
  
  This study compared the importance of age at adiposity rebound versus childhood BMI to subsequent BMI levels in a longitudinal analysis.
  
  Methods:
  
  From the electronic health records of 4.35 million children, a total of 12,228 children were selected who were examined at least once each year between ages 2 and 7 years and reexamined after age 14 years. The minimum number of examinations per child was six. Each child’s rebound age was estimated using locally weighted regression (lowess), a smoothing technique.
  
  Results:
  
  Children who had a rebound age < 3 years were, on average, 7 kg/m2 heavier after age 14 years than were children with a rebound age ≥ 7 years. However, BMI after age 14 years was more strongly associated with BMI at the rebound than with rebound age (r = 0.57 vs. −0.44). Furthermore, a child’s BMI at age 3 years provided more information on BMI after age 14 years than did rebound age. In addition, rebound age provided no information on subsequent BMI if a child’s BMI at age 6 years was known.
  
  Conclusions:
  
  Although rebound age is related to BMI after age 14 years, a child’s BMI at age 3 years provides more information and is easier to obtain.
  
  
• Subjects:
  Adiposity Adolescent Body Mass Index Child Child, Preschool Databases, Factual Electronic Health Records Humans Longitudinal Studies Obesity
• Source:
  Obesity (Silver Spring). 30(1):201-208
• Pubmed ID:
  34932881
• Pubmed Central ID:
  PMC11066771
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  30
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:04a5aaea83b964b0b622b58e89039de7c22f45e5861310d2cc80d171937c45c0
• Download URL:
  https://stacks.cdc.gov/view/cdc/155132/cdc_155132_DS1.pdf
• File Type:
  [PDF - 427.40 KB ]