Birth Outcomes Among People with Hepatitis C in Pregnancy — Three U.S. States, 2018–2021

Details

• Alternative Title:
  Matern Child Health J
• Personal Author:
  Woodworth, Kate R. ; Newton, Suzanne M. ; Tannis, Ayzsa ; Reynolds, Megan R. ; Olsen, Emily O. ; Sizemore, Lindsey ; Wingate, Heather ; Orkis, Lauren ; Reynolds, Bethany ; Longcore, Nicole ; Thomas, Nadia ; Kim, Shin Y. ; Panagiotakopoulos, Lakshmi ; Wester, Carolyn ; Delman, Dana Meaney ; Gilboa, Suzanne M. ; Tong, Van T.
• Description:
  Introduction
  
  There are limited and conflicting data regarding the impact of hepatitis C in pregnancy on adverse birth outcomes.
  
  Methods
  
  Using the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET), a large surveillance cohort, we describe birth outcomes among a cohort of people with HCV in pregnancy in total and by reported substance use.
  
  Results
  
  Among 1418 infants, 89% were born to people with reported substance use during pregnancy. The proportion born preterm was 20%, 13% were small-for-gestational age and 34% of term infants required intensive care.
  
  Conclusions
  
  Assessments of recent changes to recommendations for HCV screening in pregnancy should evaluate the impact on maternal access to care for both HCV treatment as well as comorbidities such as substance use disorder which may contribute to adverse birth outcomes.
  
  
• Subjects:
  Adult Cohort Studies Female Hepatitis C Humans Infant, Newborn Pregnancy Pregnancy Complications, Infectious Pregnancy Outcome Premature Birth United States

  More +
• Keywords:
  Adverse Pregnancy Outcomes Preterm Birth Substance Use
• Source:
  Matern Child Health J. 28(6):979-983
• Pubmed ID:
  38416334
• Pubmed Central ID:
  PMC11060891
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; CK19-1904/CK/NCEZID CDC HHSUnited States/
• Volume:
  28
• Issue:
  6
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:0e805501b04a4261f3461c30eb53493259d8e2132ed7254eee9ceb5a6a62a46a
• Download URL:
  https://stacks.cdc.gov/view/cdc/155117/cdc_155117_DS1.pdf
• File Type:
  [PDF - 330.34 KB ]