Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Holmes, A. ; Govan, J. ; Goldstein, R.
Holmes, A. ; Govan, J. ; Goldstein, R. Less -
Description:
In the past 2 decades, Burkholderia cepacia has emerged as a human pathogen causing numerous outbreaks, particularly among cystic fibrosis (CF) patients. One highly transmissible strain has spread across North America and Britain, and another between hospitalized CF and non-CF patients. Meanwhile, the organism has been developed as a biopesticide for protecting crops against fungal diseases and has potential as a bioremediation agent for breaking down recalcitrant herbicides and pesticides. However, B. cepacia is inherently resistant to multiple antibiotics; selection of strains "safe" for environmental application is not at present possible phenotypically or genotypically; molecular epidemiology and phylogenetic studies demonstrate that highly transmissible strains emerge randomly; and the organism has a capacity for rapid mutation and adaptation (facilitated by numerous insertion sequences), and a large, complex genome divided into separate chromosomes. Therefore, the widespread agricultural use of B. cepacia should be approached with caution.
Subjects:
[+]
Agriculture Burkholderia Cepacia Burkholderia Infections Cystic Fibrosis Environmental Microbiology Humans Infection Control Mutation Pest Control, Biological
Source:
Emerg Infect Dis. 4(2):221-227.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:5bf66d9737c9bcee8fdab44e1ca6dc9850aaa7952d635c2770a2fd29fa8e2861
Download URL:
https://stacks.cdc.gov/view/cdc/15485/cdc_15485_DS1.pdf
File Type:

Supporting Files

• 	9621192.nxml	txt
  	license.txt	txt

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