Seroepidemiologic studies of hantavirus infection among wild rodents in California.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Jay, M. ; Ascher, M. S. ; Chomel, B. B. ; Madon, M. ; Sesline, D. ; Enge, B. A. ; Hjelle, B. ; Ksiazek, T. G. ; Rollin, P. E. ; Kass, P. H. ; Reilly, K.
• Description:
  A total of 4,626 mammals were serologically tested for antibodies to Sin Nombre virus. All nonrodent species were antibody negative. Among wild rodents, antibody prevalence was 8.5% in murids, 1.4% in heteromyids, and < 0.1% in sciurids. Of 1,921 Peromyscus maniculatus (deer mice), 226 (11.8%) were antibody positive, including one collected in 1975. The highest antibody prevalence (71.4% of 35) was found among P. maniculatus on Santa Cruz Island, off the southern California coast. Prevalence of antibodies among deer mice trapped near sites of human cases (26.8% of 164) was significantly higher than that of mice from other sites (odds ratio = 4.5; 95% confidence interval = 1.7, 11.6). Antibody prevalence increased with rising elevation (> 1,200 meters) and correlated with a spatial cluster of hantavirus pulmonary syndrome cases in the Sierra Nevada.
• Subjects:
  Animals Antibodies, Viral Hantavirus Hantavirus Infections Humans Peromyscus Rodent Diseases
• Source:
  Emerg Infect Dis. 3(2):183-190.
• Document Type:
  Journal Article
• Place as Subject:
  California
• Location:
  North America
• Volume:
  3
• Issue:
  2
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:a5966c7415f0061abf95f2dd197e9c56cac6bd52cc70b9821a3eea2c89be41ca
• Download URL:
  https://stacks.cdc.gov/view/cdc/15393/cdc_15393_DS1.pdf
• File Type:
  [PDF - 133.88 KB ]