Seroepidemiologic studies of hantavirus infection among wild rodents in California.

Jay, M.; Ascher, M. S.; Chomel, B. B.; Madon, M.; Sesline, D.; Enge, B. A.; Hjelle, B.; Ksiazek, T. G.; Rollin, P. E.; Kass, P. H.; Reilly, K.

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Seroepidemiologic studies of hantavirus infection among wild rodents in California.

Published Date:

1997 Apr-Jun

Source:

Emerg Infect Dis. 3(2):183-190.

[PDF-133.88 KB]

Details:

Alternative Title:

Emerg Infect Dis

Personal Author:

Jay, M. ; Ascher, M. S. ; Chomel, B. B. ; Madon, M. ; Sesline, D. ; ... More ▼

Description:

A total of 4,626 mammals were serologically tested for antibodies to Sin Nombre virus. All nonrodent species were antibody negative. Among wild rodents, antibody prevalence was 8.5% in murids, 1.4% in heteromyids, and < 0.1% in sciurids. Of 1,921 Peromyscus maniculatus (deer mice), 226 (11.8%) were antibody positive, including one collected in 1975. The highest antibody prevalence (71.4% of 35) was found among P. maniculatus on Santa Cruz Island, off the southern California coast. Prevalence of antibodies among deer mice trapped near sites of human cases (26.8% of 164) was significantly higher than that of mice from other sites (odds ratio = 4.5; 95% confidence interval = 1.7, 11.6). Antibody prevalence increased with rising elevation (> 1,200 meters) and correlated with a spatial cluster of hantavirus pulmonary syndrome cases in the Sierra Nevada.

Subject:

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Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

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