i
Subglottic suction frequency and adverse ventilator-associated events during critical illness
-
7 2021
-
-
Source: Infect Control Hosp Epidemiol. 42(7):826-832
[PDF-1.15 MB]
Details:
-
Alternative Title:Infect Control Hosp Epidemiol
-
Personal Author:
-
Description:Objective
Tracheal intubation and mechanical ventilation provide essential support for patients with respiratory failure, but the course of mechanical ventilation may be complicated by adverse ventilator-associated events (VAE). VAE may be infection-associated or not. We sought to understand how the frequency of subglottic suction, an indicator of the quantity of sputum produced by ventilated patients, relates to onset of all VAE and infection-associated VAE.
Design
We performed a case-crossover study including 87 patients with VAE and evaluated 848 days in the pre-VAE period at risk for VAE.
Setting & Participants
Critically ill subjects were recruited from the medical intensive care unit of an academic medical center.
Methods
We used the number of as-needed subglottic suctioning events performed per calendar day to quantify sputum production and compared the immediate pre-VAE period to the preceding period. We used CDC surveillance definitions for VAE and to categorize whether events were infection-associated or not.
Results
Sputum quantity measured by subglottic suction frequency is greater in the period immediately prior to VAE, compared to the preceding period. However, it does not discriminate well between infection-associated VAE and VAE without associated infection.
Conclusions
Subglottic suction frequency may serve as a valuable marker of sputum quantity, and is associated with risk for VAE. However, our results require validation in a broader population of mechanically ventilated patients and intensive care settings.
-
Subjects:
-
Keywords:
-
Source:
-
Pubmed ID:33423714
-
Pubmed Central ID:PMC8272736
-
Document Type:
-
Funding:
-
Collection(s):
-
Main Document Checksum:
-
Download URL:
-
File Type:
