Securing the supply of benzathine penicillin: a global perspective on risks and mitigation strategies to prevent future shortages

Seghers, Frederic; Taylor, Melanie M.; Storey, Andrew; Dong, Jicui; Wi, Teodora C.; Wyber, Rosemary; Ralston, Kate; Nguimfack, Boniface Dongmo

doi:10.1093/inthealth/ihad087

Advanced Search

Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

Advanced Search
Custom Query

All these words:

For very narrow results

This exact word or phrase:

When looking for a specific result

Any of these words:

Best used for discovery & interchangable words

None of these words:

Recommended to be used in conjunction with other fields

Language:

Dates

Publication Date Range:

to

Document Data

Title:

Document Type:

Library

Collection:

Series:

People

Author:

Clear All

Query Builder

Query box

Clear All

For additional assistance using the Custom Query please check out our Help Page

CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

Securing the supply of benzathine penicillin: a global perspective on risks and mitigation strategies to prevent future shortages

5 01 2024
By Seghers, Frederic ; Taylor, Melanie M. ; Storey, Andrew ; ...
Source: Int Health. 16(3):279-282

Public Access Version Available on: May 01, 2025, 12:00 AM

Please check back on the date listed above.

English

Details You May Also Like

Details:

Alternative Title:

Int Health
Personal Author:

Seghers, Frederic ; Taylor, Melanie M. ; Storey, Andrew ; Dong, Jicui ; Wi, Teodora C. ; ... More +

Seghers, Frederic ; Taylor, Melanie M. ; Storey, Andrew ; Dong, Jicui ; Wi, Teodora C. ; Wyber, Rosemary ; Ralston, Kate ; Nguimfack, Boniface Dongmo Less -
Description:

Benzathine benzylpenicillin is a globally indispensable medicine. As a long-lasting injectable penicillin, it serves as the primary treatment for syphilis, group A streptococcal infections, rheumatic fever and rheumatic heart disease. A competitive market and low profit margins, compounded by limited visibility of demand, have resulted in a decreased number of active pharmaceutical ingredient (API) manufacturers. By 2016, only three Chinese API manufacturers remained, continuing to supply to the global market today. Recurring global shortages, a consequence of supply and demand imbalances, indicate underlying market risks. Therefore, the need for mitigation strategies is imperative.
Subjects:

[+]

Anti-Bacterial Agents Drug Industry Global Health Humans Penicillin G Benzathine
Keywords:

[+]

Benzathine Penicillin Drug Manufacture Medication Shortages Rheumatic Heart Disease Syphilis
Source:

Int Health. 16(3):279-282
Pubmed ID:

37787149
Pubmed Central ID:

PMC10987389
Document Type:

Journal Article
Funding:

001/WHO_/World Health OrganizationInternational/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/

001/WHO_/World Health OrganizationInternational/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/ Less -
Volume:

16
Issue:

3
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha-512:ffd5006e6a05bdf20a427442567e98c6d743423c575adcf4be037a70ce08084dc1560632670de29fb02f38c317052dcc32959a3b8974659e48f079053499e644
File Type:

Supporting Files:

No Additional Files

More +