Prevalence of indications for adult hepatitis A vaccination among hepatitis A outbreak-associated cases, Three US States, 2016–2019

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Hofmeister, Megan G. ; Weng, Mark K. ; Thoroughman, Douglas ; Thomasson, Erica D. ; McBee, Shannon ; Foster, Monique A. ; Collins, Jim ; Burkholder, Cole ; Augustine, Ryan J. ; Spradling, Philip R.
• Description:
  Background:
  
  Safe and effective hepatitis A vaccines have been recommended in the United States for at-risk adults since 1996; however, adult vaccination coverage is low.
  
  Methods:
  
  Among a random sample of adult outbreak-associated hepatitis A cases from three states that were heavily affected by person-to-person hepatitis A outbreaks, we assessed the presence of documented Advisory Committee on Immunization Practices (ACIP) indications for hepatitis A vaccination, hepatitis A vaccination status, and whether cases that were epidemiologically linked to an outbreak-associated hepatitis A case had received postexposure prophylaxis (PEP).
  
  Results:
  
  Overall, 74.1% of cases had a documented ACIP indication for hepatitis A vaccination. Fewer than 20% of epidemiologically linked cases received PEP.
  
  Conclusions:
  
  Efforts are needed to increase provider awareness of and adherence to ACIP childhood and adult hepatitis A vaccination and PEP recommendations in order to stop the current person-to-person hepatitis A outbreaks and prevent similar outbreaks in the future.
  
  
• Subjects:
  Adult Child Disease Outbreaks Hepatitis A Humans Immunization Prevalence United States Vaccination
• Keywords:
  Disease Outbreaks Hepatitis A Vaccines Postexposure Prophylaxis
• Source:
  Vaccine. 39(44):6460-6463
• Pubmed ID:
  34598818
• Pubmed Central ID:
  PMC10962283
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  39
• Issue:
  44
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:273fd38e982b11cc842c926aa3d0e901c92319f11ea123a8aeb3efb3ef321f98
• Download URL:
  https://stacks.cdc.gov/view/cdc/153540/cdc_153540_DS1.pdf
• File Type:
  [PDF - 70.04 KB ]