Malaria in the pregnant traveler

Details

• Alternative Title:
  J Travel Med
• Personal Author:
  McKinney, Kimberly L. ; Wu, Henry M. ; Tan, Kathrine R. ; Gutman, Julie R.
• Description:
  Pregnant travelers face numerous risks, notably increased susceptibility to or severity of multiple infections, including malaria. Because pregnant women residing in areas non-endemic for malaria are unlikely to have protective immunity, travel to endemic areas poses risk of severe illness and pregnancy complications, such as low birthweight and fetal loss. If travel to malaria-endemic areas cannot be avoided, preventive measures are critical. However, malaria chemoprophylaxis in pregnancy can be challenging, since commonly used regimens have varying levels of safety data and national guidelines differ. Furthermore, although chloroquine and mefloquine have wide acceptance for use in pregnancy, regional malaria resistance and non-pregnancy contraindications limit their use. Mosquito repellents, including N,N-diethyl-m-toluamide (DEET) and permethrin treatment of clothing, are considered safe in pregnancy and important to prevent malaria as well as other arthropod-borne infections such as Zika virus infection. Pregnant travelers at risk for malaria exposure should be advised to seek medical attention immediately if any symptoms of illness, particularly fever, develop.
• Subjects:
  Antimalarials Chemoprevention Chloroquine Drug Resistance Female Humans Malaria Mefloquine Pregnancy Proguanil Travel

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• Keywords:
  Atovaquone-proguanil Doxycycline Insect Repellent Malarone Mefloquine Primaquine Tafenoquine
• Source:
  J Travel Med. 27(4)
• Pubmed ID:
  32419013
• Pubmed Central ID:
  PMC10956547
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  27
• Issue:
  4
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:4a08c886daf717580a09da762204e569653b9641d31e03503941dab671565082
• Download URL:
  https://stacks.cdc.gov/view/cdc/153473/cdc_153473_DS1.pdf
• File Type:
  [PDF - 106.60 KB ]