Clinical characteristics of the West Nile fever outbreak, Israel, 2000.

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Chowers, M. Y. ; Lang, R. ; Nassar, F. ; Ben-David, D. ; Giladi, M. ; Rubinshtein, E. ; Itzhaki, A. ; Mishal, J. ; Siegman-Igra, Y. ; Kitzes, R. ; Pick, N. ; Landau, Z. ; Wolf, D. ; Bin, H. ; Mendelson, E. ; Pitlik, S. D. ; Weinberger, M.
• Description:
  West Nile (WN) virus is endemic in Israel. The last reported outbreak had occurred in 1981. From August to October 2000, a large-scale epidemic of WN fever occurred in Israel; 417 cases were confirmed, with 326 hospitalizations. The main clinical presentations were encephalitis (57.9%), febrile disease (24.4%), and meningitis (15.9%). Within the study group, 33 (14.1%) hospitalized patients died. Mortality was higher among patients >70 years (29.3%). On multivariate regressional analysis, independent predictors of death were age >70 years (odds ratio [OR] 7.7), change in level of consciousness (OR 9.0), and anemia (OR 2.7). In contrast to prior reports, WN fever appears to be a severe illness with high rate of central nervous system involvement and a particularly grim outcome in the elderly.
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Aging Child Child, Preschool Disease Outbreaks Female Fever Hospitalization Humans Male Meningitis, Viral Middle Aged West Nile Fever

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• Source:
  Emerg Infect Dis. 7(4):675-678.
• Document Type:
  Journal Article
• Place as Subject:
  Israel
• Volume:
  7
• Issue:
  4
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:813475431d7de6f2643df02ba65dc22c6fc8b6d3914a8a75deb099674091435a
• Download URL:
  https://stacks.cdc.gov/view/cdc/15184/cdc_15184_DS1.pdf
• File Type:
  [PDF - 56.09 KB ]