Determinants of Adherence to Antihypertension Medications Among Patients at a Tertiary Care Hospital in Islamabad, Pakistan, 2019

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Noreen, Nadia ; Bashir, Faiza ; Khan, Abdul Wali ; Safi, Malik Muhammad ; Lashari, Waheed Ahmad ; Hering, Dagmara
• Description:
  Introduction ; Medication nonadherence leads to poor health outcomes, frequent complications, and high economic impact. Our objective was to assess the determinants of adherence to medication regimens among patients with hypertension. ; Methods ; We conducted a cross-sectional study of patients with hypertension attending the cardiology clinic of a tertiary care hospital in Islamabad, Pakistan. Data were collected by using semistructured questionnaires. A score of 7 or 8 on the 8-item Morisky Medication Adherence Scale was classified as good adherence, 6 as moderate, and less than 6 as nonadherence. Logistic regression was performed to determine covariates associated with medication adherence. ; Results ; We enrolled 450 patients with hypertension (mean age, 54.5 y; SD, 10.6). Medication adherence was good among 115 (25.6%) patients and moderate among 165 (36.7%); 170 (37.8%) patients were nonadherent. Most patients (72.7%) had uncontrolled hypertension. Nearly half (49.6%) were unable to afford monthly medication. In bivariate analysis, nonadherence was associated with female sex (odds ratio OR, 1.44; P = .003) and long waiting times in the health care facility (OR, 2.93; P = .005); the presence of comorbidities (OR, 0.62; P = .01) was associated with good adherence. In multivariate analysis, nonadherence was associated with unaffordability of treatment (OR, 2.25; P = .002) and uncontrolled hypertension (OR, 3.16; P < .001). Good adherence determinants included adequate counseling (OR, 0.29; P < .001) and education (OR, 0.61; P = .02). ; Conclusion ; Addressing identified barriers, including medication affordability and patient counseling, should be included in Pakistan’s national policy on noncommunicable disease.
• Subjects:
  • Humans
  • Female
  • Middle Aged
  • Tertiary Care Centers
  • Cross-Sectional Studies
  • Antihypertensive Agents
  • Hypertension
  • Medication Adherence
• Source:
  Prev Chronic Dis. 2023; 20
• DOI:
  http://dx.doi.org/10.5888/pcd20.220231
• ISSN:
  1545-1151
• Pubmed ID:
  37229649
• Pubmed Central ID:
  PMC10240930
• Document Type:
  Journal Article
• Place as Subject:
  Pakistan
• Volume:
  20
• Download URL:
  https://stacks.cdc.gov/view/cdc/151011/cdc_151011_DS1.pdf
• File Type:
  [PDF - 520.59 KB]
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:bd4964911a8ea6909ac3aeff7db98337df862a9db4ba17544cb721398dcf2b96bfebe211c6c0cc0050709d87a356fa432a5bc8153e3c39121cda8d0e8f0ea249