Details:

• Alternative Title:
  Cancer
• Personal Author:
  Negoita, Serban ; Chen, Huann-Sheng ; Sanchez, Pamela V. ; Sherman, Recinda L. ; Henley, S. Jane ; ... More +

  Negoita, Serban ; Chen, Huann-Sheng ; Sanchez, Pamela V. ; Sherman, Recinda L. ; Henley, S. Jane ; Siegel, Rebecca ; Sung, Hyuna ; Scott, Susan ; Benard, Vicki B. ; Kohler, Betsy A. ; Jemal, Ahmedin ; Cronin, Kathleen Less -
• Description:
  Background:
  
  With access to cancer care services limited because of COVID-19 control measures, cancer diagnosis and treatment have been delayed. We explored changes in the counts of U.S. incident cases by cancer type, age, sex, race, and disease stage in 2020.
  
  Methods:
  
  Data were extracted from selected U.S. population-based cancer registries for diagnosis years 2015–2020 using first-submission data from the North American Association of Central Cancer Registries. Following a quality assessment, the monthly numbers of newly diagnosed cancer cases were extracted for six cancer types: colorectal, female breast, lung, pancreas, prostate, and thyroid. The observed numbers of incident cancer cases in 2020 were compared with the estimated numbers by calculating observed to expected (O/E) ratios. The expected numbers of incident cases were extrapolated using Joinpoint trend models.
  
  Results:
  
  We report an O/E ratio less than one for major screening-eligible cancer sites, indicating fewer newly diagnosed cases than expected in 2020. The O/E ratios were lowest in April 2020. For every cancer site except pancreas, Asian/Pacific Islander persons (API) had the lowest O/E ratio of any race group. O/E ratios were lower for cases diagnosed at localized stages than for cases diagnosed at advanced stages.
  
  Conclusions:
  
  Our analysis provides strong evidence for declines in cancer diagnoses, relative to the expected numbers, between March and May 2020. The declines correlate with reductions in pathology reports and are greater for cases diagnosed at in situ and localized stage, triggering concerns about potential poor cancer outcomes in the coming years, especially in API persons.
  
  
• Keywords:
  [+]

  Cancer Incidence Cancer Stage Cancer Surveillance COVID-19 COVID-19 Testing Female Humans Male Neoplasms Observed-to-expected Pandemics Pathology Reports Registries
• Source:
  Cancer. 130(1):117-127
• Pubmed ID:
  37755665
• Pubmed Central ID:
  PMC10841454
• Document Type:
  Journal Article
• Funding:
  Z99 CA999999/ImNIH/Intramural NIH HHSUnited States/ ; CA/NCI NIH HHSUnited States/ ; DP/NCCDPHP CDC HHSUnited States/

  Z99 CA999999/ImNIH/Intramural NIH HHSUnited States/ ; CA/NCI NIH HHSUnited States/ ; DP/NCCDPHP CDC HHSUnited States/ Less -
• Volume:
  130
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  [+]

  urn:sha-512:1fab23cc6a98eecf6fbb3f9a92d9ecdea7f5f6edbce654f5a8e38ccaaf30bbd53cadb0821363cdc1e9e3abb27f4b282e81966ef29ecf29b32cd9e65d84130b08
• File Type:

• Supporting Files:
  No Additional Files