Content
and Copyright
i
Pseudomonas aeruginosa, Staphylococcus aureus, and Fluoroquinolone Use
-
Published Date:
Aug 2005
Source:Emerg Infect Dis. 11(8):1197-1210.
[PDF-270.49 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Few long-term multicenter investigations have evaluated the relationships between aggregate antimicrobial drug use in hospitals and bacterial resistance. We measured fluoroquinolone use from 1999 through 2003 in a network of US hospitals. The percentages of fluoroquinolone-resistant Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus (MRSA) were obtained from yearly antibiograms at each hospital. Univariate linear regression showed significant associations between a hospital's volume of fluoroquinolone use and percent resistance in most individual study years (1999-2001 for P. aeruginosa, 1999-2002 for S. aureus). When the method of generalized estimating equations was used, a population-averaged longitudinal model incorporating total fluoroquinolone use and the previous year's resistance (to account for autocorrelation) did not show a significant effect of fluoroquinolone use on percent resistance for most drug-organism combinations, except for the relationship between levofloxacin use and percent MRSA. The ecologic relationship between fluoroquinolone use and resistance is complex and requires further study.
-
Subject:
-
Document Type:
-
Collection(s):
-
Main Document Checksum:
- File Type:
-
Supporting Files:
image/gif 
image/jpeg 
image/gif 
image/jpeg 
text/plain
text/plain
No Related Documents.
You May Also Like:
-
Published Date:Source:File Type:[PDF - 37.46 KB]
File Type:[PDF - 37.46 KB]
Published Date:Source:File Type:[PDF - 20.43 KB]
File Type:[PDF - 20.43 KB]
Published Date:Source:Description:File Type:[PDF - 28.80 KB]
File Type:[PDF - 28.80 KB]
Published Date:Source:File Type:[PDF - 17.68 KB]
File Type:[PDF - 17.68 KB]
Published Date:Source:File Type:[PDF - 299.44 KB]
File Type:[PDF - 299.44 KB]
Have Questions?
Visit CDC Info
Email
CDC-INFO
Open 24/7
CDC INFORMATION
CONNECT WITH CDC
