Alpha and beta spillover in liquid scintillation counting analysis of urine samples

Details

• Alternative Title:
  J Radioanal Nucl Chem
• Personal Author:
  Piraner, Olga ; Eardley, Karlee ; Button, Jonathan
• Description:
  Rapid detection and quantification of gross alpha/beta-emitting radionuclides by liquid scintillation counting (LSC) is vital in guiding response to a nuclear or radiological incidents. Liquid scintillation counters use signal pulse shape to discriminate alpha and beta events in samples but require precise optimization to minimize the spillover, or misclassification, of those events. In this study, samples at varying activity levels were analyzed by LSC to determine the effect of activity level, emitter type, and sample matrix on spillover. Analysis proved a matrix effect and a direct correlation of activity level on spillover percentage for both alpha and beta emitting-nuclides.
• Keywords:
  Emergency Response Gross Alpha/Beta Urine Bioassay Liquid Scintillation Counting Spillover
• Source:
  J Radioanal Nucl Chem. 332(9):3837-3844
• Pubmed ID:
  38162401
• Pubmed Central ID:
  PMC10755725
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  332
• Issue:
  9
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:339292d28f443f5b9252840b27763c221d388ad7a9207c082bc2907e835e98c2
• Download URL:
  https://stacks.cdc.gov/view/cdc/140151/cdc_140151_DS1.pdf
• File Type:
  [PDF - 1.17 MB ]