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Evaluation of the impact of meningococcal serogroup A conjugate vaccine on the childhood immunization program’s second-year-of-life vaccination coverage in Burkina Faso
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10 31 2019
Source: J Infect Dis. 220(220 Suppl 4):S233-S243 -
Alternative Title:J Infect Dis
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Personal Author:
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Description:Background:
Following successful meningococcal serogroup A conjugate vaccine (MACV) campaigns since 2010, Burkina Faso introduced MACV in March 2017 into the routine Expanded Programme for Immunization (EPI) schedule at age 15–18 months, concomitantly with second-dose measles-containing vaccine (MCV2). We examined MCV2 coverage in pre- and post-MACV introduction cohorts to describe observed changes regionally and nationally.
Methods:
A nationwide household cluster survey of children 18–41 months of age was conducted 1 year after MACV introduction. Coverage was assessed by verification of vaccination cards or recall. Two age groups were included to compare MCV2 coverage pre-MACV introduction (30–41 months) versus post-MACV introduction (18–26 months).
Results:
In total, 15,925 households were surveyed; 7,796 children were enrolled, including 3,684 30–41 months of age and 3,091 18–26 months of age. Vaccination documentation was observed for 86% of children. MACV routine coverage was 58% (95% confidence interval [CI]:56–61%) with variation by region (41–76%). MCV2 coverage was 62% (CI:59–65%) pre-MACV introduction and 67% (CI:64–69%) post-MACV introduction, an increase of 4.5% (CI:1.3–7.7%). Among children who received routine MACV and MCV2, 93% (CI:91–94%) received both at the same visit. Lack of caregiver awareness about the 15- to 18-month visit and vaccine unavailability were common reported barriers to vaccination.
Conclusion:
A small yet significant increase in national MCV2 coverage was observed 1 year post-MACV introduction. MACV/MCV2 co-administration was common. Findings will help inform strategies to strengthen second-year-of-life immunization coverage, including to address the communication and vaccine availability barriers identified.
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Pubmed ID:31671442
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Pubmed Central ID:PMC10718265
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