Presence of Antibodies against Genogroup VI Norovirus in Humans

Details

• Alternative Title:
  Virol J
• Personal Author:
  Mesquita, João Rodrigo ; Costantini, Verónica P ; Cannon, Jennifer L ; Lin, Seh-ching ; Nascimento, Maria São José ; Vinjé, Jan
• Description:
  Background
  
  Noroviruses are important enteric pathogens in humans and animals. Recently, we reported a novel canine norovirus (CaNoV) in dogs with diarrhea belonging to a new genogroup (GVI). No data are available on exposure of humans to this virus.
  
  Methods
  
  Sera from 373 small animal veterinarians and 120 age-matched population controls were tested for IgG antibodies to CaNoV by a recombinant virus like particle based enzyme-linked immunosorbent assay.
  
  Results
  
  Antibodies to CaNoV were found in 22.3% of the veterinarians and 5.8% of the control group (p < 0.001). Mean corrected OD450 values for CaNoV antibodies were significantly higher in small animal veterinarians compared to the control group.
  
  Conclusions
  
  These findings suggest that CaNoV may infect humans and small animal veterinarians are at an increased risk for exposure to this virus. Additional studies are needed to assess if this virus is able to cause disease in humans.
  
  
• Subjects:
  Research
• Source:
  Virol J. 2013; 10:176.
• Document Type:
  Journal Article
• Volume:
  10
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d7dae6a5d94f3f9fc5d6d14345d6b5c71f3d06ce902642494bd4757ef1832d82
• Download URL:
  https://stacks.cdc.gov/view/cdc/13668/cdc_13668_DS1.pdf
• File Type:
  [PDF - 717.24 KB ]