The Estimated Number and Lifetime Medical Cost of HIV Infections Attributable to Sexually Transmitted Infections Acquired in the United States in 2018: A Compilation of Published Modeling Results
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The Estimated Number and Lifetime Medical Cost of HIV Infections Attributable to Sexually Transmitted Infections Acquired in the United States in 2018: A Compilation of Published Modeling Results

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English

Details:

  • Alternative Title:
    Sex Transm Dis
  • Personal Author:
  • Description:
    Background:

    The purpose of this study was to estimate the number and lifetime medical cost of HIV infections attributable to incident sexually transmitted infections (STIs) in the United States in 2018.

    Methods:

    We combined data from published models regarding the number or percentage of HIV infections attributable to STIs with updated estimates of the lifetime medical cost per HIV infection. We used two distinct calculation methods. Our first calculation used recent estimates of the percentage of HIV infections in men who have sex with men (MSM) attributable to gonorrhea and chlamydia. Our second calculation, based on older studies, used estimates of the expected number of STI-attributable HIV infections per new STI infection, for gonorrhea, chlamydia, syphilis, and trichomoniasis.

    Results:

    Our first calculation method suggested that 2,489 (25th–75th percentile: 1,895–3,000) HIV infections in 2018 among MSM could be attributed to gonorrhea and chlamydia, at an estimated lifetime medical cost of $1.05 billion (25th–75th percentile: $0.79–1.26 billion). Our second calculation method suggested that 2,349 (25th–75th percentile: 1,948–2,744) HIV infections in the general population (including MSM) could be attributed to chlamydia, gonorrhea, syphilis, and trichomoniasis acquired in 2018, at an estimated lifetime medical cost of $0.99 billion (25th–75th percentile: $0.80–1.16 billion).

    Conclusions:

    Despite ambiguity regarding the degree to which STIs affect HIV transmission, our combination of data from published STI/HIV transmission models and an HIV lifetime medical cost model can help to quantify the estimated burden of STI-attributable HIV infections in the United States.

  • Keywords:
  • Source:
  • Pubmed ID:
    33492098
  • Pubmed Central ID:
    PMC10676007
  • Document Type:
  • Funding:
  • Volume:
    48
  • Issue:
    4
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  • Main Document Checksum:
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