Simultaneous administration of mRNA COVID-19 bivalent booster and influenza vaccines

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Kenigsberg, Tat’Yana A. ; Goddard, Kristin ; Hanson, Kayla E. ; Lewis, Ned ; Klein, Nicola ; Irving, Stephanie A. ; Naleway, Allison L. ; Crane, Bradley ; Kauffman, Tia L. ; Xu, Stanley ; Daley, Matthew F. ; Hurley, Laura P. ; Kaiser, Robyn ; Jackson, Lisa A. ; Jazwa, Amelia ; Weintraub, Eric S.
• Description:
  The U.S. Food and Drug Administration authorized use of mRNA COVID-19 bivalent booster vaccines on August 31, 2022. Currently, CDC's clinical guidance states that COVID-19 and other vaccines may be administered simultaneously. At time of authorization and recommendations, limited data existed describing simultaneous administration of COVID-19 bivalent booster and other vaccines. We describe simultaneous influenza and mRNA COVID-19 bivalent booster vaccine administration between August 31-December 31, 2022, among persons aged ≥6 months in the Vaccine Safety Datalink (VSD) by COVID-19 bivalent booster vaccine type, influenza vaccine type, age group, sex, and race and ethnicity. Of 2,301,876 persons who received a COVID-19 bivalent booster vaccine, 737,992 (32.1%) received simultaneous influenza vaccine, majority were female (53.1%), aged ≥18 years (91.4%), and non-Hispanic White (55.7%). These findings can inform future VSD studies on simultaneous influenza and COVID-19 bivalent booster vaccine safety and coverage, which may have implications for immunization service delivery.
• Subjects:
  Adolescent Adult COVID-19 Female Humans Influenza, Human Influenza Vaccines Male RNA, Messenger United States Vaccines, Combined

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• Keywords:
  Co-administration MRNA Covid-19 Bivalent Booster Vaccine Seasonal Influenza Vaccine Simultaneous Vaccination
• Source:
  Vaccine. 41(39):5678-5682
• Pubmed ID:
  37599140
• Pubmed Central ID:
  PMC10661699
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  41
• Issue:
  39
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:83240f96727e7c3d6bc66e800d1e5451ad07840a2d6db9e2aa7f58f4cde9fa2e42cd19ec4bde9f6ed3c7d0a599db1b9e1a0eb9d7b3486af0df4a4cf51e6333e9
• Download URL:
  https://stacks.cdc.gov/view/cdc/135768/cdc_135768_DS1.pdf
• File Type:
  [PDF - 297.29 KB ]