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Folic acid and prevention of spina bifida and anencephaly; 10 years after the U.S. Public Health Service recommendation
  • Published Date:
    September 13, 2002
Filetype[PDF - 1.57 MB]

  • Corporate Authors:
    National Center on Birth Defects and Developmental Disabilities (U.S.), Division of Birth Defects and Developmental Disabilities. ; Centers for Diseases Control and Prevention (U.S.) ;
  • Series:
    MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports ; v. 51, no. RR-13
  • Document Type:
  • Description:
    Introduction / J. David Erickson -- Serum folate levels among women attending family planning clinics--Georgia, 2000 / Lara C. Than, Margaret Watkins, Katherine Lyon Daniel -- Spina bifida and anencephaly prevalence--United States, 1991-2001 / T. J. Mathews, Margaret A. Honein, J. David Erickson -- Sociodemographic patterns in spina bifida birth prevalence trends--North Carolina, 1995-1999 / Robert E. Meyer, Anna-Maria Siega-Riz -- Folic acid awareness and use among women with a history of a neural tube defect pregnancy--Texas, 2000-2001 / Mark A. Canfield, James L. Anderson, D. Kim Waller, Susan E. Palmer, Celia I. Kaye.

    In September 1992, the U.S. Public Health Service (USPHS) recommended that all women capable of becoming pregnant should consume 400 microg of folic acid/day on an ongoing basis to reduce their risk for having a pregnancy affected by spina bifida and anencephaly (i.e., neural tube defects [NTDs]). The recommendation was preceded a year earlier by a CDC recommendation for women at high risk (i.e., those women who have had an earlier pregnancy affected by an NTD). The 1991 CDC recommendation stated that women at high risk should plan subsequent pregnancies and consume 4,000 microg/day of folic acid from the time they begin trying to become pregnant through the first trimester of pregnancy to reduce their risk. The 1992 USPHS recommendation specified that women at high risk should follow the general population recommendation for consumption of 400 microg/day when not trying to become pregnant.

  • Supporting Files:
    No Additional Files