Clinical Characteristics of Children With Tourette Syndrome With and Without Sleep Disorder

Details

• Alternative Title:
  Pediatr Neurol
• Personal Author:
  Ricketts, Emily J. ; Wolicki, Sara Beth ; Holbrook, Joseph R. ; Rozenman, Michelle ; McGuire, Joseph F. ; Charania, Sana N. ; Piacentini, John ; Mink, Jonathan W. ; Walkup, John T. ; Woods, Douglas W. ; Claussen, Angelika H.
  More +
• Description:
  Background: ; Sleep problems are common in children with Tourette Syndrome (TS). However, research regarding their demographic and clinical profile is limited. ; Methods: ; We examined characteristics of 114 children aged five to 17 years with a lifetime diagnosis of TS and compared children with sleep disorder (n = 32) and without sleep disorder (n = 82). Parent report from the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome provided demographics and clinical information, other diagnosed disorders, medication use, TS severity, and impairment. ; Results: ; More children with TS with sleep disorder were from households with lower parental education (P < 0.01) and poverty (P = 0.04); had other diagnoses (P = 0.03), including obsessive-compulsive disorder (P < 0.01), oppositional defiant disorder or conduct disorder (P < 0.01), attention-deficit/hyperactivity disorder (ADHD) (P = 0.02), and autism (P = 0.03); and had ever used TS medication (P = 0.01) than children with TS without sleep disorder. More children with TS with sleep disorder had severe TS symptoms (P <0.01), tic-related impairment (P<0.01), and severe ADHD symptoms (P < 0.01) compared with children with TS without sleep disorder. ; Conclusions: ; Findings suggest greater parent-reported impact and tic-related interference in children with TS with sleep disorder compared with TS without sleep disorder. Results underscore the importance of monitoring and intervention for TS exacerbations, other diagnosed disorders, and medication use, and consideration of socioeconomic context in sleep disorder management and prevention in children with TS.
• Subjects:
  • Humans
  • Child
  • Tourette Syndrome
  • Tics
  • Comorbidity
  • Attention Deficit Disorder with Hyperactivity
  • Obsessive-Compulsive Disorder
• Keywords:
  • Tourette syndrome
  • Tics
  • Sleep disorder
  • Comorbidity
  • Impairment
• Source:
  Pediatr Neurol. 141:18-24
• Pubmed ID:
  36736236
• Pubmed Central ID:
  PMC10590926
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/ ; K23 MH113884/MH/NIMH NIH HHSUnited States/ ; T32 MH073517/MH/NIMH NIH HHSUnited States/
• Volume:
  141
• Download URL:
  https://stacks.cdc.gov/view/cdc/134523/cdc_134523_DS1.pdf
• File Type:
  [PDF - 350.49 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:d51dcd813b6574c267a3b118ab434f7a14e0d5eb63fae39a655066c39d107a22