Food Sensitivities in a Diverse Nationwide Cohort of Veterans with Interstitial Cystitis/Bladder Pain Syndrome

Details

• Alternative Title:
  J Urol
• Personal Author:
  Jarman, Aubrey ; Janes, Jessica L. ; Shorter, Barbara ; Moldwin, Robert ; De Hoedt, Amanda M. ; Barbour, Kamil E. ; Kim, Jayoung ; Freedland, Stephen J. ; Anger, Jennifer T.
• Description:
  Purpose:
  
  Prior studies suggest that certain foods exacerbate interstitial cystitis/bladder pain syndrome symptoms. However, these studies were limited in size and demographics. We assessed the presence of diet sensitivities among patients with interstitial cystitis/bladder pain syndrome and compared them with patients with other pelvic pain conditions and healthy controls.
  
  Materials and Methods:
  
  We identified Veterans Affairs patients nationwide by querying ICD-9/10 codes for IC/BPS. Patients were assigned to IC/BCP, other pelvic pain (OPP), or healthy control (HC) cohorts after chart review. We mailed all patients the Shorter-Moldwin Food Sensitivity Questionnaire (SMQ) to evaluate the self-perceived effects of specific foods/beverages on urinary symptoms and/or bladder pain.
  
  Results:
  
  In the IC/BPS cohort, 70% had ≥1 food sensitivity vs. 37% of the OPP cohort and 32% of HC (p<0.001). The average number of sensitivities were similar between OPP and HC cohorts, which were significantly less than in IC/BPS patients. IC/BPS patients were more sensitive to acidic, spicy foods, and certain beverages vs. other cohorts (all p<0.001). Within the IC/BPS cohort, Black patients had significantly higher alcoholic and non-caffeinated beverages sensitivity than whites. Black patients did report significantly worsened urinary urgency than whites (p<0.05).
  
  Conclusions:
  
  In a diverse population of veterans, IC/BPS patients had significantly more food sensitivities than those without IC/BPS. This suggests that food sensitives could be suggestive of IC/BPS, which could make the SMQ a helpful diagnostic tool and aid in distinguishing IC/BPS from conditions often confused with IC/BPS.
  
  
• Keywords:
  Cystitis, Interstitial Food Sensitivities Humans Interstitial Cystitis/ Bladder Pain Syndrome Pelvic Pain
• Source:
  J Urol. 209(1):216-224
• Pubmed ID:
  36001744
• Pubmed Central ID:
  PMC10542818
• Document Type:
  Journal Article
• Funding:
  U01 DP006079/DP/NCCDPHP CDC HHSUnited States/
• Volume:
  209
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:47cdf7bca7bddba23bbf78077d3c1bdc1eba40e2abcb87336537f0fe2399c5da
• Download URL:
  https://stacks.cdc.gov/view/cdc/133828/cdc_133828_DS1.pdf
• File Type:
  [PDF - 148.10 KB ]