Severity Outcomes Associated with SARS-CoV-2 XBB Variants, an observational analysis

Klein, Eili Y.; Fall, Amary; Norton, Julie M.; Eldesouki, Raghda E.; Abdullah, Omar; Han, Lijie; Yunker, Madeline; Mostafa, Heba H.

doi:10.1016/j.jcv.2023.105500

i

Severity Outcomes Associated with SARS-CoV-2 XBB Variants, an observational analysis

Supporting Files

8 2023
By Klein, Eili Y. ; Fall, Amary ; Norton, Julie M. ; ...

File Language:

English

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Alternative Title:

J Clin Virol
Personal Author:

Klein, Eili Y. ; Fall, Amary ; Norton, Julie M. ; Eldesouki, Raghda E. ; Abdullah, Omar ; Han, Lijie ; Yunker, Madeline ; Mostafa, Heba H.
Description:

The rapidity with which SARS-CoV-2 XBB variants rose to predominance has been alarming. We used a large cohort of patients diagnosed with Omicron infections between September 2022 and mid-February 2023 to evaluate the likelihood of admission or need for supplemental oxygen in patients infected with XBB variants. Our data showed no significant association between XBB or XBB.1.5 infections and admissions. Older age groups, lack of vaccination, immunosuppression and underlying heart, kidney, and lung disease showed significant associations with hospitalization.
Subjects:

Aged Cluster Analysis COVID-19 Hospitalization Humans SARS-CoV-2
Source:

J Clin Virol. 165:105500
Pubmed ID:

37290254
Pubmed Central ID:

PMC10232717
Document Type:

Journal Article
Funding:

U01 CK000589/CK/NCEZID CDC HHSUnited States/ ; UM1 AI068613/AI/NIAID NIH HHSUnited States/ ; U54 HL143541/HL/NHLBI NIH HHSUnited States/ ; HHSN272201400007C/AI/NIAID NIH HHSUnited States/ ; U01CK000589/ACL/ACL HHSUnited States/
Volume:

165
Collection(s):

CDC Public Access
Main Document Checksum:

urn:sha-512:06f0ecabea059472bdf754ba1c9e0f007fe605cf4bebb83fb63325f809c1e699cbcf50d6be8c5301abfcba8da487987e2c8aaa87bb30cba3b6e0da1b1b19c1df
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https://stacks.cdc.gov/view/cdc/133464/cdc_133464_DS1.pdf
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[PDF - 81.17 KB ]

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