Feasibility of jet injector use during inactivated poliovirus vaccine house-to-house vaccination campaigns

Details

• Alternative Title:
  Vaccine
• Personal Author:
  Farag, Noha H. ; Mansour, Ziad ; Torossian, Lina ; Said, Racha ; Snider, Cynthia J. ; Ehrhardt, Derek
• Description:
  Background:
  
  To attain high coverage during polio vaccination campaigns, an outreach house-to-house strategy is used to administer oral poliovirus vaccine. Administering an injectable vaccine house-to-house requires a skilled work force and increases risks of needle stick injuries. Needle-free injection devices provide a safer alternative to needles and syringes for administering injectable vaccines. We evaluated the feasibility and acceptability of a needle-free injection device to administer injectable poliovirus vaccine during a house-to-house vaccination outreach activity.
  
  Methods:
  
  Vaccination teams administered injectable poliovirus vaccine using the Pharmajet® needle-free intramuscular jet injector to children ages 6–59 months in 766 homes. Data on the feasibility of using the jet injector in an outreach campaign setting and the acceptability of the jet injector by caregivers and vaccinators were collected.
  
  Results:
  
  A total of 993 injections were administered. Vaccinators faced challenges during device preparation in 16% (n = 158) of injections; challenges were related to problems loading the injector and not having a flat surface to use for setup of the injector. Among 32 vaccinators interviewed after the vaccination campaign, the main reported advantage of the device was absence of sharps disposal (91%) while the main reported disadvantage was unacceptability by parents (90%) which was related to the vaccine, not the device.
  
  Conclusions:
  
  The needle-free jet injector was feasible for use in house-to-house campaigns. Acceptability by vaccinators was low as 81% stated that the jet injector was not easier to use than needle and syringe. Parental refusal related to frequent polio vaccination campaigns was the biggest challenge. In addition, novelty of the device posed a challenge to teams as they needed to reassure parents about safety of the device. To take full advantage of the ability to take injectable vaccines door-to-door during vaccination campaigns using a needle-free jet injector device, tailored social mobilization efforts are needed ahead of campaigns.
  
  
• Keywords:
  Child, Preschool Female Humans Infant Injectable Vaccine Injections, Jet Male Needle-free Injection Polio Poliomyelitis Poliovirus Poliovirus Vaccine, Inactivated Supplementary Vaccination Activities Vaccination Campaigns

  More +
• Source:
  Vaccine. 36(32 Pt B):4935-4938
• Pubmed ID:
  29980387
• Pubmed Central ID:
  PMC10514717
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  36
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:e7a5300ddd38ef0485466b61d7aaf01eb019151fca14df8f95f327debffee8ec
• Download URL:
  https://stacks.cdc.gov/view/cdc/133280/cdc_133280_DS1.pdf
• File Type:
  [PDF - 111.74 KB ]