Details:

Alternative Title:
Occup Environ Med
Personal Author:
Kurth, Laura ; Mazurek, Jacek M ; Blackley, David J
Kurth, Laura ; Mazurek, Jacek M ; Blackley, David J Less -
Description:
Objectives

Mesothelioma is a rare, aggressive cancer caused by exposure to asbestos fibres. Mesothelioma patients who receive trimodal therapy (chemotherapy, surgical resection and radiation) survive longer than those who receive two or fewer therapy modalities. This study analyses the 2016–2019 Medicare claims data to estimate the burden of malignant mesothelioma and describe therapy patterns (when available) among continuously enrolled fee-for-service (FFS; Medicare parts A and B) beneficiaries.

Methods

We analysed claims and enrolment information from 42 529 117 FFS Medicare beneficiaries using three mesothelioma case definitions (broad, intermediate and narrow) with varying levels of diagnostic requirements. Results are presented as ranges of values for the three definitions.

Results

Among FFS beneficiaries, 8213–19 036 beneficiaries with mesothelioma were identified depending on the case definition. The annual prevalence per 100 000 beneficiaries ranged from 8.8 in 2016 (narrow) to 31.3 in 2019 (broad) and annual incidence per 100 000 beneficiaries ranged from 4.5 in 2019 (narrow) to 12.6 in 2017 (broad). Depending on the mesothelioma case definition, 41.8%–81.5% had available therapy claim information indicating that 7.6%–11.3% received chemotherapy alone, 1.3%–1.5% received radiation alone, and 14.3%–27.0% underwent surgery only, with 4.6%–10.5% receiving all three therapy modalities.

Conclusions

Mesothelioma was a prevalent disease among FFS Medicare beneficiaries during 2016–2019, and a limited proportion of beneficiaries received all three therapy modalities. Medicare data build on findings from cancer registry data to enhance our understanding of the mesothelioma burden and therapy patterns.


Keywords:
[+]
Aged Fee-for-Service Plans Humans Incidence Medicare Mesothelioma, Malignant Prevalence United States
Source:
Occup Environ Med. 80(2):86-92
Pubmed ID:
36635096
Pubmed Central ID:
PMC10423587
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHSUnited States/
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:cadd4c2dfa52fbeb59cfbca5cb7c9f333186f2468860327af651f96d148a5a41
Download URL:
https://stacks.cdc.gov/view/cdc/132022/cdc_132022_DS1.pdf
File Type:

Supporting Files

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  	nihms-1919964-f0001.jpg	jpeg
  	nihms-1919964.nxml	xml
  	NIHMS1919964-supplement-1.pdf	pdf

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