Cardiovascular Disease and Lifestyle Choices: Spotlight on Circadian Rhythms and Sleep

Details

• Alternative Title:
  Prog Cardiovasc Dis
• Personal Author:
  Figueiro, Mariana G. ; Pedler, David
• Description:
  The advent of electric lighting in the built environment has radically transformed the human experience of light and darkness, which is often insufficient to stimulate and synchronize the circadian system to the day-night cycle. The lack of circadian system entrainment leads to poor sleep and could be an important biophysical mechanism underlying increased incidence of certain types of diseases, including cardiovascular (CV) disease (CVD). This contribution proposes to carve out a niche for including daily exposures to light and darkness among lifestyle factors for reducing the risk and progression of CVD. The fundamental workings of the human circadian system and its primary outputs are described. The discussion then progresses to light's effects on the circadian system and its outputs, and how threats to circadian health pose risks for CV health. The contribution concludes with simple recommendations for incorporating regular, robust daily exposures in lifestyle adjustments to combat CVD risks and progression.
• Keywords:
  Cardiovascular Disease Cardiovascular Diseases Circadian Rhythm Circadian Rhythms Disruption Circadian System Darkness Humans Light Melatonin Sleep
• Source:
  Prog Cardiovasc Dis. 77:70-77
• Pubmed ID:
  36841493
• Pubmed Central ID:
  PMC10225333
• Document Type:
  Journal Article
• Funding:
  R01 DK128972/DK/NIDDK NIH HHSUnited States/ ; R01 OH010668/OH/NIOSH CDC HHSUnited States/ ; R01OH010668/ACL/ACL HHSUnited States/
• Volume:
  77
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:25ff7c41b3a0624327bd780017cbdbd5ef3de6466c60ffffc3ac09cae46e904a
• Download URL:
  https://stacks.cdc.gov/view/cdc/129367/cdc_129367_DS1.pdf
• File Type:
  [PDF - 983.63 KB ]