Rapid Determination of 235U/238U in Urine Using Q-ICP-MS by a Simple Dilute-and-Shoot Approach

Details

• Alternative Title:
  J Radioanal Nucl Chem
• Personal Author:
  Xiao, Ge ; Button, Jonathan
• Description:
  The measurement of uranium (U) isotope ratios in urine provides valuable information about the source of U exposure in humans and can be vitally important in a radiological emergency. This method provides rapid and accurate results for |U/|U at |U concentrations as low as 0.42 ng/L, which is equivalent to ~200 ng/L of total U for a depleted U (DU) at a |U/|U ratio of ~0.002. The results are within 6% of Certified Reference Materials target values and agree with Department of Defense Armed Forces Institute of Pathology inter-laboratory comparison target values with a bias range of -6.9% to 7.6%.
• Subjects:
  Article Emergency Response ICP-MS Total Uranium Uranium Isotope Ratio Urine
• Source:
  J Radioanal Nucl Chem. 332(1):185-191
• Pubmed ID:
  37206056
• Pubmed Central ID:
  PMC10193512
• Document Type:
  Journal Article
• Funding:
  CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  332
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:dde05ea3cd907fce929031f6dc7ede4182f4e45cda50e681c995b6fd49328725
• Download URL:
  https://stacks.cdc.gov/view/cdc/128767/cdc_128767_DS1.pdf
• File Type:
  [PDF - 669.56 KB ]