First Case of High-Level Azithromycin-Resistant Neisseria gonorrhoeae in North Carolina

Palavecino, Elizabeth L.; Kilic, Abdullah; Schmerer, Matthew W.; Dobre-Buonya, Oana; Toler, Cindy; McNeil, Candice J.

doi:10.1097/OLQ.0000000000001149

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First Case of High-Level Azithromycin-Resistant Neisseria gonorrhoeae in North Carolina

5 2020
By Palavecino, Elizabeth L. ; Kilic, Abdullah ; Schmerer, Matthew W. ; ...
http://dx.doi.org/10.1097/OLQ.0000000000001149
Source: Sex Transm Dis. 47(5):326-328

[PDF-175.31 KB]

English

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Details:

Alternative Title:

Sex Transm Dis
Personal Author:

Palavecino, Elizabeth L. ; Kilic, Abdullah ; Schmerer, Matthew W. ; Dobre-Buonya, Oana ; Toler, Cindy ; ... More +

Palavecino, Elizabeth L. ; Kilic, Abdullah ; Schmerer, Matthew W. ; Dobre-Buonya, Oana ; Toler, Cindy ; McNeil, Candice J. Less -
Description:

We report on the first high-level azithromycin-resistant Neisseria gonorrhoeae isolate (minimum inhibitory concentration, ≥256 μg/mL) in North Carolina isolated from a pharyngeal swab of a 33-year-old HIV-negative man who has sex with men. In addition, the isolate was found to be susceptible to cefixime, ceftriaxone, and penicillin and resistant to tetracycline. By whole-genome sequencing, the strain was assigned as MLST ST9363, NG-MAST ST5035, and a novel NG-STAR sequence type, ST1993.
Subjects:

[+]

Adult Anti-Bacterial Agents Article Azithromycin Cefixime Ceftriaxone Drug Resistance, Bacterial Gonorrhea HIV Seronegativity Homosexuality, Male Humans Male Microbial Sensitivity Tests Multilocus Sequence Typing Neisseria Gonorrhoeae North Carolina Penicillins Pharynx Tetracycline Whole Genome Sequencing
Source:

Sex Transm Dis. 47(5):326-328
Pubmed ID:

32073548
Pubmed Central ID:

PMC10186591
Document Type:

Journal Article
Funding:

CC999999/ImCDC/Intramural CDC HHSUnited States/
Volume:

47
Issue:

5
Collection(s):

CDC Public Access
Main Document Checksum:

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urn:sha256:45c1ff7a7e9b57e3edc1073cd66d0ef788c409a31ccebd85d39ed959a9ba73fb
Download URL:

https://stacks.cdc.gov/view/cdc/128494/cdc_128494_DS1.pdf
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