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Comparable pregnancy outcomes for HIV-uninfected and HIV-infected women on antiretroviral treatment in Kenya
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9 04 2022
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Source: J Infect Dis. 226(4):678-686
[PDF-120.54 KB]
Details:
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Alternative Title:J Infect Dis
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Description:Background
The impact of Human Immunodeficiency Virus (HIV) on pregnancy outcomes for women on antiretroviral therapy (ART) in sub-Saharan Africa remains unclear.
Methods
Pregnant women in Kenya were enrolled in the second trimester and followed up to delivery. We estimated effects of treated HIV with three pregnancy outcomes: loss, premature birth, and low birthweight and factors associated with HIV-positive status.
Results
Of 2,113 participants, 311 (15%) were HIV-infected and on ART. Ninety-one of 1,762 (5%) experienced a pregnancy loss, 169/1,725 (10%) a premature birth (<37 weeks), and 74/1,317 (6%) had a low birthweight newborn (<2500g).
Conclusion
Currently treated HIV was not significantly associated with adverse pregnancy outcomes. HIV-infected women, however, had a higher prevalence of other factors associated with adverse pregnancy outcomes.
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Pubmed ID:35403695
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Pubmed Central ID:PMC10155227
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Volume:226
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Issue:4
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