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Interaction profile for : chlorpyrifos, lead, mercury, and methylmercury
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August 2006
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[PDF-1.20 MB]
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Description:Chlorpyrifos, lead, and mercury/methylmercury were chosen as the subject for this interaction profile because of the likelihood of co-exposure and because of concerns about neurological effects in children co-exposed to these chemicals. Chlorpyrifos is an organophosphorus insecticide widely used for agricultural and indoor and outdoor residential applications in the United States. Its use, however, is being phased out. Mercury (metallic and inorganic) and lead are released to the environment from hazardous waste sites and from mining, smelting, and industrial activities. Metallic and inorganic mercury can be transformed by microorganisms into methylmercury, which bioaccumulates in the food chain. For the general population, and particularly for subsistence fishers and hunters, the most important pathway of exposure to mercury is ingestion of methylmercury in foods. Fish (including tuna, a food commonly eaten by children), other seafood, and marine mammals contain the highest concentrations. Lead, present in the environment primarily as divalent lead compounds, also contaminates the environment due to its release from mining and from deteriorating lead paint and its historical use in gasoline.
ip11.pdf
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Pages in Document:ix, 93 numbered pages
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