Strict Glycemic Control and Mortality Risk Among US adults with Type 2 Diabetes

Details

• Alternative Title:
  J Diabetes Complications
• Personal Author:
  Davila, Evelyn P. ; Florez, Hermes ; Trepka, Mary Jo ; Fleming, Lora E. ; Niyonsenga, Theophile ; Lee, David J. ; Parkash, Jai
• Description:
  Objective:
  
  Assess the relationships between strict HbA1c levels and mortality risk among adults with type 2 diabetes by age, insulin therapy, and hypertension comorbidity.
  
  Methods:
  
  Data of adult participants with type 2 diabetes from the third National Health and Nutrition Examination Survey (1988–1994) and its linked mortality file (with follow-up death up to 2000) were used.
  
  Results:
  
  Having strict glycemic control (i.e. HbA1c ≤ 6.5%) was associated with a lower risk of mortality (hazards ratio= 0.69 [95% confidence interval=0.48–0.98]). However, among those with strict glycemic control levels, statistically significant results were not found.
  
  Conclusion:
  
  Reaching strict glycemic control levels in the general US population with type 2 diabetes appears to be associated with lower mortality. Further research is needed as to how strict glycemic control affects certain diabetic groups.
  
  
• Subjects:
  Adolescent Adult Aged Aged, 80 And Over Age Factors Comorbidity Cross-Sectional Studies Diabetes Mellitus, Type 2 Drug Monitoring Female Follow-Up Studies Glycated Hemoglobin Health Surveys Humans Hypertension Hypoglycemic Agents Insulin Male Middle Aged Mortality Risk Young Adult

  More +
• Source:
  J Diabetes Complications. 25(5):289-291
• Pubmed ID:
  21658973
• Pubmed Central ID:
  PMC10038225
• Document Type:
  Journal Article
• Funding:
  R01 OH003915/OH/NIOSH CDC HHSUnited States/
• Place as Subject:
  United States
• Volume:
  25
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:9b76107dfe20a73ad6c43b4d0e23e29f0c79f1827276d1816d1e7ffdf36e91fb
• Download URL:
  https://stacks.cdc.gov/view/cdc/126195/cdc_126195_DS1.pdf
• File Type:
  [PDF - 57.72 KB ]