Risk Factors for Suffocation and Unexplained Causes of Infant Deaths

Details

• Alternative Title:
  Pediatrics
• Personal Author:
  Parks, Sharyn E. ; DeSisto, Carla L. ; Kortsmit, Katherine ; Bombard, Jennifer M. ; Shapiro-Mendoza, Carrie K.
• Description:
  BACKGROUND:
  
  Observational studies have improved our understanding of the risk factors for sudden infant death syndrome, but separate examination of risk for sleep-related suffocation and unexplained infant deaths has been limited. We examined the association between unsafe infant sleep practices and sudden infant deaths (sleep-related suffocation and unexplained causes including sudden infant death syndrome).
  
  METHODS:
  
  We conducted a population-based case-control study using 2016 to 2017 Centers for Disease Control and Prevention data. Controls were liveborn infants from the Pregnancy Risk Assessment Monitoring System; cases were from the Sudden Unexpected Infant Death Case Registry. We calculated risk factor prevalence among cases and controls and crude and adjusted odds ratios.
  
  RESULTS:
  
  We included 112 sleep-related suffocation cases with 448 age-matched controls and 300 unexplained infant death cases with 1200 age-matched controls. Adjusted odds for sleep- related suffocation ranged from 18.7 (95% confidence interval [CI]: 6.8–51.3) among infants not sharing a room with their mother or caregiver to 1.9 (95% CI: 0.9–4.1) among infants with nonsupine sleep positioning. Adjusted odds for unexplained death ranged from 7.6 (95% CI: 4.7–12.2) among infants not sharing a room with their mother or caregiver to 1.6 (95% CI: 1.1–2.4) among nonsupine positioned infants.
  
  COCLUSIONS:
  
  We confirmed previously identified risk factors for unexplained infant death and independently estimated risk factors for sleep-related suffocation. Significance of associations for suffocation followed similar patterns but was of larger magnitude. This information can be used to improve messaging about safe infant sleep.
  
  
• Keywords:
  Asphyxia Case-Control Studies Female Humans Infant Infant Mortality Risk Factors Sleep Sudden Infant Death
• Source:
  Pediatrics. 151(1)
• Pubmed ID:
  36464994
• Pubmed Central ID:
  PMC9942004
• Document Type:
  Journal Article
• Funding:
  CC999999/Intramural CDC HHSUnited States/
• Volume:
  151
• Issue:
  1
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha256:9b6c80b087add7cecdd7296e6ec747ba3b17bbca429832f26bed6b0862c434ac
• Download URL:
  https://stacks.cdc.gov/view/cdc/124942/cdc_124942_DS1.pdf
• File Type:
  [PDF - 123.43 KB ]