Details:

Alternative Title:
MMWR Morb Mortal Wkly Rep
Personal Author:
Pastula, Daniel M. ; Copeland, Matthew J. ; Hannan, Markus C. ; Rapaka, Samuel ; Kitani, Takashi ; ... More +
Pastula, Daniel M. ; Copeland, Matthew J. ; Hannan, Markus C. ; Rapaka, Samuel ; Kitani, Takashi ; Kleiner, Elizabeth ; Showler, Adrienne ; Yuen, Cindy ; Ferriman, Elizabeth M. ; House, Jennifer ; O’Brien, Shannon ; Burakoff, Alexis ; Gupta, Bhavik ; Money, Kelli M. ; Matthews, Elizabeth ; Beckham, J. David ; Chauhan, Lakshmi ; Piquet, Amanda L. ; Kumar, Rebecca N. ; Tornatore, Carlo S. ; Padgett, Kia ; O’Laughlin, Kevin ; Mangla, Anil T. ; Kumar, Princy N. ; Tyler, Kenneth L. ; O’Connor, Siobhán M. Less -
Description:
Monkeypox virus (MPXV) is an orthopoxvirus in the Poxviridae family. The current multinational monkeypox outbreak has now spread to 96 countries that have not historically reported monkeypox, with most cases occurring among gay, bisexual, and other men who have sex with men (1,2). The first monkeypox case in the United States associated with this outbreak was identified in May 2022 in Massachusetts (1); monkeypox has now been reported in all 50 states, the District of Columbia (DC), and one U.S. territory. MPXV is transmitted by close contact with infected persons or animals; infection results in a febrile illness followed by a diffuse vesiculopustular rash and lymphadenopathy. However, illness in the MPXV current Clade II outbreak has differed: the febrile prodrome is frequently absent or mild, and the rash often involves genital, anal, or oral regions (3,4). Although neuroinvasive disease has been previously reported with MPXV infection (5,6), it appears to be rare. This report describes two cases of encephalomyelitis in patients with monkeypox disease that occurred during the current U.S. outbreak. Although neurologic complications of acute MPXV infections are rare, suspected cases should be reported to state, tribal, local, or territorial health departments to improve understanding of the range of clinical manifestations of and treatment options for MPXV infections during the current outbreak.
Subjects:
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Encephalomyelitis Exanthema Homosexuality, Male Humans Male Monkeypox Monkeypox Virus Sexual And Gender Minorities
Source:
MMWR Morb Mortal Wkly Rep. 71(38):1212-1215
Pubmed ID:
36136957
Pubmed Central ID:
PMC9531567
Document Type:
Journal Article
Genre:
Full Report
Place as Subject:
Colorado ; District of Columbia ; United States
Colorado ; District of Columbia ; United States Less -
Collection(s):
Morbidity and Mortality Weekly Report (MMWR)
Main Document Checksum:
[+]
urn:sha256:9eeff779f59d19529e4f6316ac02e8d7251ac3e175b4a0d9299a7d44506ad610
Download URL:
https://stacks.cdc.gov/view/cdc/122545/cdc_122545_DS1.pdf
File Type:

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