Details:

Alternative Title:
AIDS
Personal Author:
CREPAZ, Nicole ; SONG, Ruiguang ; LYSS, Sheryl B. ; HALL, H. Irene
CREPAZ, Nicole ; SONG, Ruiguang ; LYSS, Sheryl B. ; HALL, H. Irene Less -
Description:
Objective:

To examine changes in the lengths of time from HIV infection to diagnosis (Infx-to-Dx) and from diagnosis to first viral suppression (Dx-to-VS), two periods during which HIV can be transmitted.

Design:

Data from the National HIV Surveillance System (NHSS) for persons who were aged ≥13 years at the time of HIV diagnosis during 2014–2018 and resided in one of 33 U.S. jurisdictions with complete laboratory reporting.

Methods:

The date of HIV infection was estimated based on a CD4-depletion model. Date of HIV diagnosis, and dates and results of first CD4 test and first viral suppression (<200 copies/mL) after diagnosis were reported to NHSS through December 2019. Trends for Infx-to-Dx and Dx-to-VS intervals were examined using estimated annual percentage change.

Results:

During 2014–2018, among persons aged ≥13 years, 133,413 HIV diagnoses occurred. The median length of infx-to-Dx interval shortened from 43 months (2014) to 40 months (2018), a 1.5% annual decrease (7.0% relative change over the 5-year period). The median length of Dx-to-VS interval shortened from 7 months (2014) to 4 months (2018), an 11.4% annual decrease (42.9% relative change over the 5-year period). Infx-to-Dx intervals shortened in only some subgroups, while Dx-to-VS intervals shortened in all groups by sex, transmission category, race/ethnicity, age, and CD4 count at diagnosis.

Conclusion:

The shortened Infx-to-Dx and Dx-to-VS intervals suggest progress in promoting HIV testing and earlier treatment; however, diagnosis delays continue to be substantial. Further shortening both intervals and eliminating disparities are needed to achieve Ending the HIV Epidemic goals.


Subjects:
[+]
Article CD4 Lymphocyte Count Ethnicity HIV Diagnosis Delay HIV Infection HIV Infections HIV Testing Humans Time To Viral Suppression United States Viral Load
Source:
AIDS. 35(13):2181-2190
Pubmed ID:
34172670
Pubmed Central ID:
PMC9647140
Document Type:
Journal Article
Funding:
CC999999/ImCDC/Intramural CDC HHSUnited States/
Collection(s):
CDC Public Access
Main Document Checksum:
[+]
urn:sha256:30b73e6a72bf003b17b9a4e159106c9702fd573d64cfa0c31d022d6383174757
Download URL:
https://stacks.cdc.gov/view/cdc/122194/cdc_122194_DS1.pdf
File Type:

Supporting Files

• nihms-1838905.nxml

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