Geographic Variation in Obesity at the State Level in the All of Us Research Program

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Clark, Cheryl R. ; Chandler, Paulette D. ; Zhou, Guohai ; Noel, Nyia ; Achilike, Confidence ; Mendez, Lizette ; O’Connor, George T. ; Smoller, Jordan W. ; Weiss, Scott T. ; Murphy, Shawn N. ; Ommerborn, Mark J. ; Karnes, Jason H. ; Klimentidis, Yann C. ; Jordan, Christina D. ; Hiatt, Robert A. ; Ramirez, Andrea H. ; Loperena, Roxana ; Mayo, Kelsey ; Cohn, Elizabeth ; Ohno-Machado, Lucila ; Boerwinkle, Eric ; Cicek, Mine ; Schully, Sheri D. ; Mockrin, Stephen ; Gebo, Kelly A. ; Karlson, Elizabeth W.
• Description:
  Introduction
  
  National obesity prevention strategies may benefit from precision health approaches involving diverse participants in population health studies. We used cohort data from the National Institutes of Health All of Us Research Program (All of Us) Researcher Workbench to estimate population-level obesity prevalence.
  
  Methods
  
  To estimate state-level obesity prevalence we used data from physical measurements made during All of Us enrollment visits and data from participant electronic health records (EHRs) where available. Prevalence estimates were calculated and mapped by state for 2 categories of body mass index (BMI) (kg/m2): obesity (BMI >30) and severe obesity (BMI >35). We calculated and mapped prevalence by state, excluding states with fewer than 100 All of Us participants.
  
  Results
  
  Data on height and weight were available for 244,504 All of Us participants from 33 states, and corresponding EHR data were available for 88,840 of these participants. The median and IQR of BMI taken from physical measurements data was 28.4 (24.4– 33.7) and 28.5 (24.5–33.6) from EHR data, where available. Overall obesity prevalence based on physical measurements data was 41.5% (95% CI, 41.3%–41.7%); prevalence of severe obesity was 20.7% (95% CI, 20.6–20.9), with large geographic variations observed across states. Prevalence estimates from states with greater numbers of All of Us participants were more similar to national population-based estimates than states with fewer participants.
  
  Conclusion
  
  All of Us participants had a high prevalence of obesity, with state-level geographic variation mirroring national trends. The diversity among All of Us participants may support future investigations on obesity prevention and treatment in diverse populations.
  
  
• Subjects:
  Body Mass Index Humans Obesity Obesity, Morbid Population Health Prevalence
• Source:
  Prev Chronic Dis. 2021; 18
• DOI:
  http://dx.doi.org/10.5888/pcd18.210094
• ISSN:
  1545-1151
• Pubmed ID:
  34941480
• Pubmed Central ID:
  PMC8718125
• Document Type:
  Journal Article
• Funding:
  OT2 OD026556/OD/NIH HHSUnited States/ ; U2C OD023196/OD/NIH HHSUnited States/ ; OT2 OD025315/OD/NIH HHSUnited States/ ; OT2 OD026551/OD/NIH HHSUnited States/ ; U24 OD023121/OD/NIH HHSUnited States/ ; OT2 OD026552/OD/NIH HHSUnited States/ ; OT2 OD026549/OD/NIH HHSUnited States/ ; OT2 OD025337/OD/NIH HHSUnited States/ ; OT2 OD025277/OD/NIH HHSUnited States/ ; OT2 OD026555/OD/NIH HHSUnited States/ ; OT2 OD026550/OD/NIH HHSUnited States/ ; OT2 OD026553/OD/NIH HHSUnited States/ ; OT2 OD023205/OD/NIH HHSUnited States/ ; OT2 OD025276/OD/NIH HHSUnited States/ ; OT2 OD026557/OD/NIH HHSUnited States/ ; OT2 OD026554/OD/NIH HHSUnited States/ ; U24 OD023163/OD/NIH HHSUnited States/ ; OT2 OD023206/OD/NIH HHSUnited States/ ; U24 OD023176/OD/NIH HHSUnited States/ ; OT2 OD026548/OD/NIH HHSUnited States/
• Place as Subject:
  United States
• Location:
  North America
• Volume:
  18
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:6cb6a2e2f7480b29d9ef22cfaf499ad5e36d00d7c40b572cc3cf5c7e28812baa8173b30fc27bba6fe1a1827f4deab48c581fbbb757548cdd935b4cec3e48cd62
• Download URL:
  https://stacks.cdc.gov/view/cdc/122179/cdc_122179_DS1.pdf
• File Type:
  [PDF - 606.40 KB ]