Point prevalence of Hip Symptoms, Radiographic, And Symptomatic OA at Five Time Points: The Johnston County Osteoarthritis Project, 1991–2018

Details

• Alternative Title:
  Osteoarthr Cartil Open
• Personal Author:
  Nelson, Amanda E. ; Hu, David ; Arbeeva, Liubov ; Alvarez, Carolina ; Cleveland, Rebecca J. ; Schwartz, Todd A. ; Murphy, Louise B. ; Helmick, Charles G. ; Callahan, Leigh F. ; Renner, Jordan B. ; Jordan, Joanne M. ; Golightly, Yvonne M.
  More +
• Description:
  Objective: ; To describe the point prevalence of hip symptoms, radiographic hip osteoarthritis (rHOA), severe rHOA, and symptomatic rHOA (sxHOA) at five time points in the longitudinal, population-based Johnston County Osteoarthritis Project (JoCoOA). ; Design: ; Data were from 3068 JoCoOA participants who attended up to five study visits (1991–2018). Standardized supine pelvis radiographs were read by a single, expert musculoskeletal radiologist with high reliability. The four outcomes were: 1) self-reported hip symptoms: “On most days, do you have pain, aching, or stiffness in your right/left hip?”; 2) rHOA: Kellgren-Lawrence grade (KLG) of 2–4; 3) severe rHOA: KLG of 3–4; and 4) sxHOA: both symptoms and rHOA in the same joint. Weighted point prevalence and 95% confidence intervals (CI) were generated overall and by age group (45–54, 55–64, 65–74, 75+ years), sex, race (Black/White), and body mass index (BMI; 18.5–24.9; 25–29.9; 30+ kg/m2). ; Results: ; At the most recent follow-up (2017–2018), the point prevalence (%) of hip symptoms, rHOA, severe rHOA, and sxHOA were 30% (95% CI 25%, 35%), 53% (95% CI 48%, 58%), 9% (95% CI 6%, 12%), and 15% (95% CI 11%, 19%), respectively. RHOA and severe rHOA were most prevalent in those 75+ years. Women were more likely than men to have hip symptoms and sxHOA. No consistent trends were noted by race or BMI. ; Conclusion: ; These updated point prevalence estimates demonstrate a large and increasing burden of HOA in the general population, particularly with aging. Black and White individuals were affected similarly in this cohort.
• Keywords:
  • Hip osteoarthritis
  • prevalence
  • sex differences
  • radiography
• Source:
  Osteoarthr Cartil Open. 4(2)
• Pubmed ID:
  36118130
• Pubmed Central ID:
  PMC9479672
• Document Type:
  Journal Article
• Funding:
  P60 AR049465/AR/NIAMS NIH HHSUnited States/ ; U01 DP006266/DP/NCCDPHP CDC HHSUnited States/ ; P60 AR064166/AR/NIAMS NIH HHSUnited States/ ; U01DP003206/ACL/ACL HHSUnited States/ ; P30 AR072580/AR/NIAMS NIH HHSUnited States/
• Volume:
  4
• Issue:
  2
• Download URL:
  https://stacks.cdc.gov/view/cdc/121446/cdc_121446_DS1.pdf
• File Type:
  [PDF - 468.91 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:c7c90bae9c1f36cae11c7ac9c96a8a35ca084d9577858120ba6d98da07bbd323486a572d849d8dd8cd7d79a915791becc6f5f420d3dddc0b49ceda9889cc1fbd