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Factors Associated with Colorectal Cancer Prevalence Among Long-Haul Truck Drivers in the United States
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9 2022
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Source: Am J Health Promot. 36(7):1142-1151
[PDF-106.38 KB]
Details:
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Alternative Title:Am J Health Promot
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Personal Author:
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Description:Purpose:
To determine the age-adjusted association between colorectal cancer (CRC) risk factors and CRC prevalence among long-haul truck drivers (aged 21–85), after adjustment for age.
Design:
Pooled cross-sectional analysis using Commercial Driver Medical Exam (CDME) data. Setting. National survey data from January 1, 2005, to October 31, 2012.
Participants:
47,786 commercial motor vehicle drivers in 48 states.
Measures:
CRC prevalence was the primary outcome; independent variables included demographics, body mass index (BMI), and concomitant medical conditions.
Analysis:
Kruskal-Wallis tests to analyze continuous variables; Fischer’s exact tests to analyze categorical variables; univariate and multivariable logistic regression for rare events (Firth method) to quantify the association between the independent variables of interest and CRC prevalence. Odds ratios (ORs) and 95% confidence intervals (CIs) were adjusted for age, gender, years with current employer, year of exam, and BMI in a multivariate logistic regression.
Results:
Many factors were statistically significant. Obesity (OR = 3.14; 95% CI = 1.03–9.61) and increasing age (OR = 1.10 per year; 95% CI = 1.07–1.13) were significantly associated with CRC prevalence. Truckers with 4 or more concomitant medical conditions were significantly more likely to have CRC (OR = 7.03; 95% CI = 1.83–27.03).
Conclusions:
Our findings highlight mutable risk factors and represent an opportunity for intervention that may decrease CRC morbidity and mortality among truck drivers, a unique population in the United States estimated to live up to 16 years less than the general population.
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Subjects:
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Source:
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Pubmed ID:35410488
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Pubmed Central ID:PMC9420779
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Funding:
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Volume:36
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Issue:7
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