Tips for adequate collection of a lesion specimen from a suspect monkeypox virus case
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Tips for adequate collection of a lesion specimen from a suspect monkeypox virus case

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    Vigorous swabbing of lesion specimens maximizes the probability of achieving accurate diagnostic results. Specimens that do not contain enough human DNA may lead to inconclusive PCR test results, with no positive or negative result.

    Inconclusive results necessitate patients being sampled again which can delay diagnosis. Follow the instructions below to make sure your specimens are adequate for testing. While vigorous swabbing on the surface of a lesion should collect enough viral DNA, more viral DNA can be found in crusts when present. Recommended infection prevention and control practices, including the use of personal protective equipment (PPE), for caring for a patient with suspected or confirmed monkeypox infection should be used during specimen collection: What Healthcare Professionals Should Know. Unroofing or aspiration of lesions (or otherwise using sharp instruments for monkeypox testing) is not necessary, nor recommended due to the risk for sharps injury.

    CS333812-A | 08/23/2022

    MPox-AdequateSpecimenCollection_508.pdf

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