The magnitude and distribution of iron deficiency using serum/plasma ferritin among preschool children and non-pregnant women: a multi-country analysis

Details

• Alternative Title:
  Med Res Arch
• Personal Author:
  Mei, Zuguo ; Grummer-Strawn, Laurence M.
• Description:
  Background:
  
  In 2004, World Health Organization (WHO) recommended the use of serum ferritin as a primary indicator of iron deficiency. However, there was limited data on the magnitude and distribution of iron deficiency based on ferritin.
  
  Objective:
  
  To describe the prevalence of iron deficiency as measured by serum/plasma ferritin in different regions of the world and its relationship with demographic and health indicators.
  
  Methods:
  
  Data from the Biomarkers Reflecting Inflammation and Nutrition Determinants of Anemia and the WHO Vitamin and Mineral Nutrition Information System Micronutrients Database were used for this analysis. Unadjusted and inflammation-adjusted low ferritin prevalence were calculated for both databases. The prevalence of low ferritin among preschool children and non-pregnant women was examined according to its relationship with national gross domestic product (GDP), infant mortality rate (IMR), and anemia rate.
  
  Results:
  
  In children, the median inflammation-adjusted prevalence of low ferritin was 35.3% (1st and 3rd quartiles: 17.5% and 48.1%). In non-pregnant women, the median inflammation-adjusted prevalence of low ferritin was 28.4% (1st and 3rd quartiles: 21.4% and 42.0%). For both children and women, the correlation between the prevalence of low ferritin and GDP, IMR, or anemia was consistently stronger using inflammation-adjusted prevalences than when using unadjusted prevalences.
  
  Conclusions:
  
  The quartile values of low ferritin prevalence for children and non-pregnant women could be used to define the severity of ferritin as a public health problem.
  
  
• Keywords:
  Children Ferritin Iron Deficiency Public Health Significance Women
• Source:
  Med Res Arch. 7(12)
• Pubmed ID:
  35919338
• Pubmed Central ID:
  PMC9341006
• Document Type:
  Journal Article
• Funding:
  001/WHO_/World Health OrganizationInternational/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  7
• Issue:
  12
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:f2a2c64ebcfd3f75cb3c253acde379885fbfdb82092543cc650760a76cccb7e56cb868f1a88a433e4d2a94cfb4464abe4f99350ac673d350bb30bb8d3b68c68e
• Download URL:
  https://stacks.cdc.gov/view/cdc/119956/cdc_119956_DS1.pdf
• File Type:
  [PDF - 1.00 MB ]