Breastfeeding and post-perinatal infant deaths in the United States, A national prospective cohort analysis
Advanced Search
Select up to three search categories and corresponding keywords using the fields to the right. Refer to the Help section for more detailed instructions.

Search our Collections & Repository

For very narrow results

When looking for a specific result

Best used for discovery & interchangable words

Recommended to be used in conjunction with other fields

Dates

to

Document Data
Library
People
Clear All
Clear All

For additional assistance using the Custom Query please check out our Help Page

i

Breastfeeding and post-perinatal infant deaths in the United States, A national prospective cohort analysis

Filetype[PDF-287.20 KB]


English
Details Supporting Files You May Also Like

Details:

  • Alternative Title:
    Lancet Reg Health Am
  • Personal Author:
  • Description:
    Background

    Reducing infant mortality is a major public health goal. The potential impact of breastfeeding on infant deaths is not well studied in the United States (US).

    Methods

    We analyzed linked birth–death certificates for 3,230,500 US births that occurred in 2017, including 6,969 post-perinatal deaths from 7–364 days of age as the primary outcome, further specified as late-neonatal (7–27 days) or post-neonatal (28–364 days) deaths. The primary exposure was ‘ever breastfed’ obtained from birth certificates. Multiple logistic regression examined associations of ever breastfeeding with post-perinatal deaths and specific causes of deaths, controlling for maternal and infant factors.

    Findings

    We observed an adjusted reduced odds ratio (AOR)= 0·74 with 95% confidence intervals (CI)=0·70–0·79 for the association of breastfeeding initiation with overall infant deaths (7–364 days), AOR=0·60 (0·54–0·67) for late-neonatal deaths, and AOR=0·81 (0·76–0·87) for post-neonatal deaths. In race/ethnicity-stratified analysis, significant associations of breastfeeding initiation with reduced odds of overall infant deaths were observed for Hispanics [AOR=0·64 (0·55–0·74)], non-Hispanic Whites [AOR=0·75 (0·69–0·81)], non-Hispanic Blacks [AOR=0·83 (0·75–0·91)], and non-Hispanic Asians [AOR=0·51 (0·36–0·72)]. Across racial/ethnic groups, effect sizes for late-neonatal deaths were consistently larger than those for post-neonatal deaths. Significant effects of breastfeeding initiation were observed for deaths due to infection [AOR=0·81(0·69–0·94)], Sudden Unexpected Infant Death [AOR=0·85 (0·78–0·92)], and necrotizing enterocolitis [AOR=0·67 (0·49–0·90)].

    Interpretation

    Breastfeeding initiation is significantly associated with reduced odds of post-perinatal infant deaths in multiple racial and ethnic groups within the US population. These findings support efforts to improve breastfeeding in infant mortality reduction initiatives.

  • Keywords:
  • Source:
    Lancet Reg Health Am. 5
  • Pubmed ID:
    35911656
  • Pubmed Central ID:
    PMC9335131
  • Document Type:
    Journal Article
  • Funding:
    CC999999/ImCDC/Intramural CDC HHSUnited States/
  • Volume:
    5
  • Collection(s):
  • Main Document Checksum:
  • Download URL:
  • File Type:

You May Also Like

Checkout today's featured content at stacks.cdc.gov