Biological Sample Preparation Collaboration Project; detection of Bacillus anthracis spores in soil : final study report
Published Date:January 2011
Corporate Authors:National Homeland Security Research Center (U.S.) ; National Center for Emerging and Zoonotic Infectious Diseases (U.S.) ; United States, Environmental Protection Agency.
Hazardous Waste Site Remediation
Isolation & Purification
Bacillus Anthracis/Decontamination/United States
Bacillus Anthracis/Isolation & Purification
Hazardous Waste Site Remediation/United States
Funding:IA#DW 75-92259701 (CDC IA# Cl10-001)
Description:"Following the terrorist events of 2001, the U.S. Environmental Protection Agency's (EPA) mission was expanded to meet critical needs related to homeland security. Presidential Directives identified EPA as the primary federal agency responsible for the country's water supplies and for decontamination following a chemical, biological, and/or radiological attack. To provide scientific and technical support for EPA to meet this expanded role, EPA's National Homeland Security Research Center (NHSRC) was established. The NHSRC research program is focused on conducting research and delivering products that improve the capability of the Agency to carry out its homeland security responsibilities. As a part of its long-term goals, NHSRC has been charged with delivery of detection techniques that will enable the rapid characterization of threats, identification of specific contaminants to protect workers, and development of plans for recovery operations. Substantial effort and resources have been invested in the development of molecular assays and culture techniques for pathogens; however, initial sample collection and preparation methodologies lag behind in development. To bridge this critical data gap, EPA collaborated with the Centers for Disease Control and Prevention to develop and optimize an immunomagnetic separation (IMS) method for isolation of Bacillus anthracis (BA) spores from soil. The developed BAIMS method will support environmental remediation and recovery activities. This report summarizes the experimental development of the method and the corresponding study results that move EPA one step closer to achieving our homeland security mission, and our overall mission of protecting human health and the environment." - p. v
U.S. Environmental Protection Agency (EPA), National Homeland Security Research Center and the Centers for Disease Control and Prevention (CDC), National Center for Emerging and Zoonotic Infectious Diseases (Proposed), under IA#DW 75-92259701 (CDC IA# Cl10-001), collaborated in the development of the analysis procedure described here.
Supporting Files:No Additional Files
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