Association Between Anthropometric Risk Factors and Metabolic Syndrome Among Adults in India: A Systematic Review and Meta-Analysis of Observational Studies

Details

• Journal Article:
  Preventing Chronic Disease (PCD)
• Personal Author:
  Krishnamoorthy, Yuvaraj ; Rajaa, Sathish ; Murali, Sharan ; Sahoo, Jayaprakash ; Kar, Sitanshu Sekhar
• Description:
  Introduction
  
  Several studies have explored the effect of anthropometric risk factors on metabolic syndrome. However, no systematic effort has explored the effect of overweight and obesity on the prevalence of metabolic syndrome in India. Thus, we undertook a meta-analysis to estimate the effect of anthropometric risk factors on the prevalence of metabolic syndrome.
  
  Methods
  
  We searched databases PubMed Central, EMBASE, MEDLINE, and Cochrane library and search engines ScienceDirect and Google Scholar, from January 1964 through March 2021. We used the Newcastle–Ottawa scale to assess the quality of published studies, conducted a meta-analysis with a random-effects model, and reported pooled odds ratios (OR) with 95% CIs.
  
  Results
  
  We analyzed 26 studies with a total of 37,965 participants. Most studies had good to satisfactory quality on the Newcastle–Ottawa scale. Participants who were overweight (pooled OR, 5.47; 95% CI, 3.70–8.09) or obese (pooled OR, 5.00; 95% CI, 3.61–6.93) had higher odds of having metabolic syndrome than those of normal or low body weight. Sensitivity analysis showed no significant variation in the magnitude or direction of outcome, indicating the lack of influence of a single study on the overall pooled estimate.
  
  Conclusion
  
  Overweight and obesity are significantly associated with metabolic syndrome. On the basis of evidence, clinicians and policy makers should implement weight reduction strategies among patients and the general population.
  
  
• Subjects:
  Adult Humans Metabolic Syndrome Obesity Overweight Risk Factors
• Source:
  Prev Chronic Dis. 2022; 19
• DOI:
  http://dx.doi.org/10.5888/pcd19.210231
• ISSN:
  1545-1151
• Pubmed ID:
  35512304
• Pubmed Central ID:
  PMC9109643
• Document Type:
  Journal Article
• Genre:
  Systematic Review
• Place as Subject:
  India
• Location:
  Asia
• Volume:
  19
• Collection(s):
  Preventing Chronic Disease
• Main Document Checksum:
  urn:sha-512:d4c503c892b81e7b714e3750ed7db567f53d8a8af88f46c8033a924f75cb91b88dbd35f2e9eb044955cd1030a86fdc99cfb7e9178e446978920b1285bd2b0c27
• Download URL:
  https://stacks.cdc.gov/view/cdc/117822/cdc_117822_DS1.pdf
• File Type:
  [PDF - 729.41 KB ]